808 nm laser induced photothermal effect on Sm3+/Nd3+ doped NaY(WO4)2 microstructures

Photothermal therapy is a new minimally invasive treatment technology, which has attracted worldwide attention in treatment of cancer. Herein, we developed Sm3+/Nd3+ doped NaY(WO4)(2) microstructures as the temperature generation system during the photothermal conversion process. Er3+/Yb3+ doped NaYF4 commercial phosphor was used as temperature probe for studying on the photothermal behavior in Sm3+/Nd3+ doped NaY(WO4)(2) microstructures. It was found that the energy transfer can be achieved between Sm3+ ion and Nd3+ ion, and the higher laser excitation current resulted in higher sample temperature. Moreover, the sample with higher Sm3+ doping concentration exhibited more obvious photothermal effect when excited by 808 nm laser. We presented here an idea for rare earth doped microcrystals targeted physical cancer therapy and highlighted the promise of using this kind of microcrystals for cancer theranostics. (C) 2016 Elsevier B.V. All rights reserved.