Journal
SENSORS AND ACTUATORS B-CHEMICAL
Volume 239, Issue -, Pages 993-1002Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2016.08.083
Keywords
Screen printed carbon electrode; Voltammetry; Neurotransmitters; Uric acid; Tryptophan
Funding
- University Grant Commission, New Delhi
- Ministry of Human Resource Development, New Delhi
- National Research Foundation of Korea [2015R1A2A1A13027762] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Ask authors/readers for more resources
A novel and sensitive electrochemical method has been developed for the simultaneous determination of dopamine (DA) and 5-hydroxytryptamine (5-HT) using graphene (GR) and poly 4-amino-3-hydroxy-1-naphthalenesulfonic acid modified screen printed carbon sensor. The electrochemical measurements were studied using cyclic voltammetry, square wave voltammetry, whereas the surface morphology of the modified sensor was characterized by Electrochemical Impedance Spectroscopy and Field Emission scanning electron microscopy. The fabricated sensor facilitated the analysis of DA and 5-HT in the concentration range 0.05100 mu M and 0.05150 mu M with the detection limit of 2 nM and 3 nM respectively. The fabricated sensor has been explored for the determination of 5-HT in the plasma samples and the selectivity of the proposed work has been proved by the analysis of DA and 5-HT in the presence of common metabolites present in biological fluids. The analytical applicability of the fabricated sensor has also been successfully demonstrated for the simultaneous detection of DA and 5-HT in the pharmacological formulations, human urine and blood samples. (C) 2016 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available