Self immolative dioxetane based chemiluminescent probe for H2O2 detection

Chemiluminescent detection of H2O2 has been achieved by using self immolative dioxetane based probe which enables the signal amplification via disassembly of two chemiluminogenic modules at the same time in response to single analyte. Upon treatment of the probe with H2O2, boronate ester was deprotected subsequently to trigger the decomposition of 1,2-dioxetane ring via CIEEL mechanism which results in light emission as a selective sign of H2O2. (C) 2016 Elsevier B.V. All rights reserved.