Journal
SENSORS
Volume 17, Issue 11, Pages -Publisher
MDPI
DOI: 10.3390/s17112689
Keywords
surface-enhanced Raman spectroscopy; specificity; selectivity; chemical reaction; antibody; aptamer; molecularly imprinted polymers; microfluidics
Funding
- National Natural Science Foundation of China [21475088]
- Science and Technology Commission of Shanghai Municipality [14ZR1430200]
- International Joint Laboratory on Resource Chemistry (IJLRC)
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Surface-enhanced Raman spectroscopy (SERS) is a powerful technique for the discrimination, identification, and potential quantification of certain compounds/organisms. However, its real application is challenging due to the multiple interference from the complicated detection matrix. Therefore, selective/specific detection is crucial for the real application of SERS technique. We summarize in this review five selective/specific detection techniques (chemical reaction, antibody, aptamer, molecularly imprinted polymers and microfluidics), which can be applied for the rapid and reliable selective/specific detection when coupled with SERS technique.
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