Journal
MATERIALS CHEMISTRY FRONTIERS
Volume 1, Issue 1, Pages 73-79Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6qm00066e
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Funding
- University of Regensburg
- Deutsche Forschungsgemeinschaft (DFG) [DI 1748/3-1]
- SINCHEM Joint Doctorate Programme selected under the Erasmus Mundus Action 1 Programme [FPA 2013-0037]
- DFG
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In this work, gelatin was crosslinked with oxidized alginate in the presence of borax yielding a hybrid biohydrogel system with the ability to self-repair upon mechanical damage. A judicious balance between concentration, stoichiometric ratio of the two biopolymers and gelatin source was found necessary to achieve optimal self-healing properties of these biohydrogels. The pH was found to have a major influence on the reconstruction of the damaged hydrogel interface, confirming that the dynamic Schiff base linkages between the amine groups of gelatin and the aldehyde groups of oxidized alginate play a fundamental role on the healing process of the hybrid gels.
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