4.7 Article

Adverse associations between maternal and neonatal cadmium exposure and birth outcomes

Journal

SCIENCE OF THE TOTAL ENVIRONMENT
Volume 575, Issue -, Pages 581-587

Publisher

ELSEVIER
DOI: 10.1016/j.scitotenv.2016.09.016

Keywords

Cadmium; Birth outcomes; Cord blood; Urine; Newborns

Funding

  1. National Natural Science Foundation of China [NSFC-STINT 8151101192]
  2. Joint China-Sweden Mobility Programme of the Swedish Foundation for International Cooperation in Research and Higher Education [STINT CH2015-6145]
  3. Shanghai Project 3-Year Action [GWIV-27.3]

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Effects of low-level cadmium(Cd) exposure during early life on fetal growth remain unclear. Our aim was to evaluate whether Cd exposure in maternal urine and umbilical cord blood was associated with birth size parameters. A birth cohort study including 1073 mother-newborn pairs was conducted from 2009 to 2010 in an agricultural population in China. Cd concentrations were analyzed in both cord blood and maternal urine. Generalized linear models were performed to determine associations between maternal and neonatal exposure to Cd and birth indicators, including birth weight, length, head circumference and ponderal index. The median (25th to 75th percentile) value of Cd concentration in maternal urine and umbilical cord blood was 0.19 (0.08, 1.00) mu g/L and 0.40 (

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