Journal
DEVELOPMENTAL NEUROBIOLOGY
Volume 78, Issue 2, Pages 80-92Publisher
WILEY
DOI: 10.1002/dneu.22538
Keywords
hearing; deafness; myelin; auditory; circuits
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Funding
- National Institute on Deafness and Other Communication Disorders [R01DC004820]
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Myelin allows for the rapid and precise timing of action potential propagation along neuronal circuits and is essential for healthy auditory system function. In this article, we discuss what is currently known about myelin in the auditory system with a focus on the timing of myelination during auditory system development, the role of myelin in supporting peripheral and central auditory circuit function, and how various myelin pathologies compromise auditory information processing. Additionally, in keeping with the increasing recognition that myelin is dynamic and is influenced by experience throughout life, we review the growing evidence that auditory sensory deprivation alters myelin along specific segments of the brain's auditory circuit. (c) 2017 Wiley Periodicals, Inc. Develop Neurobiol 78: 80-92, 2018
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