Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 360, Issue 2, Pages 379-384Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201701244
Keywords
Regiocontrol; Amidation; Isoquinolone; Pyridone; Iridium(III)
Categories
Funding
- SERB, India [YSS/2014/000383, SR/FST/CSII-026/2013]
- CSIR, India
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Iridium(III)-catalyzed highly regiocontrolled C3/C8 amidation of isoquinolones and C6 amidation of 2-pyridones has been successfully accomplished with various azides. The optimized method is operationally simple with a broad substrate scope. The protocol has been found to be scalable.
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