4.8 Article

Artificial Molecular Machines in Nanotheranostics

Journal

ACS NANO
Volume 12, Issue 1, Pages 7-12

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acsnano.7b07851

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Funding

  1. Intramural Research Program of the National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health
  2. National Natural Science Foundation of China [51673171]

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Due to their dynamic nature and excellent stimuli-responsiveness resulting from noncovalent driving forces, artificial molecular machines (AMMs) show great promise in cancer theranostics. In this Perspective, we introduce the potential applications of AMMs in controlled drug delivery, bioorthogonal catalysis, imaging, and cell membrane permeabilization, with the goal of enhancing cancer diagnosis and therapy. We expect this preliminary discussion will gamer multidisciplinary interest from scientists to advance AMMs and to expand their fixture clinical applications.

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