4.7 Article

Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia

Journal

EMERGING INFECTIOUS DISEASES
Volume 24, Issue 3, Pages 579-583

Publisher

CENTERS DISEASE CONTROL
DOI: 10.3201/eid2403.170151

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Funding

  1. Russian Foundation for Basic Research [16-34-60163]
  2. St. Petersburg State University [1.38.253.2015, 1.52.1647.2016]

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Whole-genome analysis of Mycobacterium tuberculosis isolates collected in Russia (N = 71) from patients with tuberculous spondylitis supports a detailed characterization of pathogen strain distributions and drug resistance phenotype, plus distinguished occurrence and association of known resistance mutations. We identify known and novel genome determinants related to bacterial virulence, pathogenicity, and drug resistance.

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