Journal
ENVIRONMENTAL RESEARCH
Volume 137, Issue -, Pages 419-423Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.envres.2015.01.010
Keywords
Phthalates; Obesity; Diabetes; Insulin resistance; Beta-cell function; Oral glucose tolerance test
Funding
- University of Antwerp [FA020000/2/3565]
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Phthalates are potentially involved in the development of type 2 diabetes mellitus. In a cohort of 123 obese subjects, 10 phthalate metabolites were analyzed. An oral glucose tolerance test was performed and various estimates of insulin resistance and beta-cell function were calculated. After adjustment for age, physical activity level, smoking behavior, medication use and body mass index, several phthalate metabolites were linked to markers of glucose tolerance and insulin resistance. (C) 2015 Elsevier Inc. All rights reserved.
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