4.4 Article

Aluminum exposure for 60 days at human dietary levels impairs spermatogenesis and sperm quality in rats

Journal

REPRODUCTIVE TOXICOLOGY
Volume 73, Issue -, Pages 128-141

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.reprotox.2017.08.008

Keywords

Metal; Reproductive adverse effects; Sperm quality

Funding

  1. Conselho Nacional de Desenvolvimento Cientifico e Tecnologico [CNPq 406715/2013-0, 203503/2015-5]
  2. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior
  3. Programa Nacional de Cooperactio Academica
  4. Proreitoria de Pesquisa-Universidade Federal do Pampa [10.134.14]
  5. Spanish Goverment [MINECO - AGL2012-32387, CSIC - Intramural 2015701028]

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Concerns about environmental aluminum (Al) and reproductive health have been raised. We investigated the effects of Al exposure at a human relevant dietary level and a high level exposure to Al. Experiment 1 (Lower level) rats were treated orally for 60 days: a) controls - ultrapure water; b) aluminum at 1.5 mg/1

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