Journal
REPORTS ON PROGRESS IN PHYSICS
Volume 80, Issue 3, Pages -Publisher
IOP Publishing Ltd
DOI: 10.1088/1361-6633/aa574a
Keywords
immunology; statistical physics; virology
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Funding
- Ragon Institute of MGH, MIT, Harvard
- NIH through Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery [UM1AI100663]
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Vaccination has saved more lives than any other medical procedure. Pathogens have now evolved that have not succumbed to vaccination using the empirical paradigms pioneered by Pasteur and Jenner. Vaccine design strategies that are based on a mechanistic understanding of the pertinent immunology and virology are required to confront and eliminate these scourges. In this perspective, we describe just a few examples of work aimed to achieve this goal by bringing together approaches from statistical physics with biology and clinical research.
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