Journal
ACS OMEGA
Volume 3, Issue 2, Pages 2049-2057Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsomega.7b01839
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Funding
- Iowa State University
- GMAP fellowship from Iowa State University
- French Ministry of Higher Education, Research and Innovation (MESRI)
- Black and Veatch Developing a world of difference faculty fellowship
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This article presents a magnetically actuated two-way, three-position (+, 0, -), paper-based microfluidic valve that includes a neutral position (0). the first of its kind. The system is highly robust, customizable, and fully automated. The advent of a neutral position and the ability to precisely control switching frequencies establish a new platform for highly controlled fluid flows in paper-based wicking microfluidic devices. The potential utility of these valves is demonstrated in automated, programmed, patterning of dyed liquids in a wicking device akin to a colorimetric assay but with a programmed fluid/reagent delivery. These valves are fabricated using facile methods and thus remain cost-effective for adoption into affordable point-of-care/bioanalytical devices.
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