4.4 Review

Implementation of Good Laboratory Practices (GLP) in basic scientific research: Translating the concept beyond regulatory compliance

Journal

REGULATORY TOXICOLOGY AND PHARMACOLOGY
Volume 89, Issue -, Pages 20-25

Publisher

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.yrtph.2017.07.010

Keywords

Good laboratory practices; Regulatory toxicology; Research in basic science; Reliability; Reproducibility

Funding

  1. National Institute of Pharmaceutical Education and Research (NIPER)
  2. S.A.S. Nagar

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The principles of Good Laboratory Practices (GLPs) are mainly intended for the laboratories performing studies for regulatory compliances. However, today GLP can be applied to broad disciplines of science to cater to the needs of the experimental objectives, generation of quality data and assay reproducibility. Considering its significance, it can now be applied in academics; industries as well as government set ups throughout the world. GLP is the best way to promote the reliability, reproducibility of the test data and hence facilitates the international acceptability. Now it is high time to translate and implement the concept of GLP beyond regulatory studies. Thus, it can pave the way for better understanding of scientific problems and help to maintain a good human and environmental health. Through this review, we have made an attempt to explore the uses of GLP principles in different fields of science and its acceptability as well as looking for its future perspectives. (C) 2017 Elsevier Inc. All rights reserved.

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