4.3 Article

Soulieoside R: A New Cycloartane Triterpenoid Glycoside from Souliea vaginata

Journal

RECORDS OF NATURAL PRODUCTS
Volume 12, Issue 1, Pages 95-100

Publisher

ACG PUBLICATIONS
DOI: 10.25135/rnp.10.17.06.103

Keywords

Souliea vaginata; cycloartane triterpenoid; soulieoside R; cytotoxicity

Funding

  1. Twelfth Five-Year Significant New Drugs Created Science and Technology Major Projects [2012ZX09301-002-001-026]
  2. Huaihua University Program [ZWX2016-11]
  3. Opening Project of Zhejiang Provincial Top Key Discipline of Pharmaceutical Sciences [YKFJ3-012]
  4. Fundamental Research Funds for the Key Laboratory of Research and Utilization of Ethnomedicinal Plant Resources of Hunan Province [YYZW2015-7]

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A new cycloartane triterpenoid glycoside, named soulieoside R, was isolated from the rhizomes of Souliea vaginata. Its structure was characterized by comprehensive analyses of H-1, C-13 NMR, COSY, HSQC, HMBC, NOESY spectroscopic, and HRESIMS mass spectrometric data, as well as chemical methods. The new compound showed weak inhibitory activity against three human cancer cell lines.

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