4.3 Article

Modeling-based determination of physiological parameters of systemic VOCs by breath gas analysis, part 2

Journal

JOURNAL OF BREATH RESEARCH
Volume 12, Issue 3, Pages -

Publisher

IOP PUBLISHING LTD
DOI: 10.1088/1752-7163/aab2b6

Keywords

modeling; breath gas analysis; volatile organic compounds (VOCs); metabolic rates; production rates; acetone

Funding

  1. Austrian Science Fund (FWF) [P24736-B23]
  2. Austrian Research Promotion Agency (FFG)
  3. European Union's Horizon research and innovation program [644031]
  4. government of Vorarlberg (Austria)

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In a recent paper (Unterkofler et al 2015 J. Breath Res. 9 036002) we presented a simple two compartment model which describes the influence of inhaled concentrations on exhaled breath concentrations for volatile organic compounds (VOCs) with small Henry constants. In this paper we extend this investigation concerning the influence of inhaled concentrations on exhaled breath concentrations for VOCs with higher Henry constants. To this end we extend our model with an additional compartment which takes into account the influence of the upper airways on exhaled breath VOC concentrations.

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