Journal
RADIOLOGIC CLINICS OF NORTH AMERICA
Volume 55, Issue 6, Pages 1251-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.rcl.2017.06.010
Keywords
Ovarian cancer; Cancer screening; Randomized trials; Transvaginal ultrasound
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Ovarian cancer has a high mortality, attributed to its typically advanced stage at detection. Despite much effort to identify an effective approach for ovarian cancer screening, to date no screening test has proven to reduce ovarian cancer mortality. The natural history of ovarian cancer is reviewed a s well as data from the largest trials of ovarian cancer screening. Currently, no North American society recommends routine ovarian cancer screening; some societies recommend consideration of screening with pelvic ultrasound and CA-125 in women at high risk, although its use in this setting is not supported by data demonstrating a mortality benefit.
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