Journal
FOODS
Volume 7, Issue 5, Pages -Publisher
MDPI
DOI: 10.3390/foods7050072
Keywords
phytochemicals; nanoparticles; controlled release; improved functionality; health; smart-formulations
Categories
Funding
- Spanish Ministry of Science and Innovation (MICINN) [AGL2016-80247-C2-1-R, AGL2016-75332-C2-1-R, AGL2017-83386-R]
- CNRS [PICS-2015-261141]
- Postdoctoral Contract (Juan de la Cierva de Incorporacion) from the Ministry of Economy, Industry, and Competitiveness of Spain [ICJI-2015-25373]
Ask authors/readers for more resources
Nanotechnology is a field of research that has been stressed as a very valuable approach for the prevention and treatment of different human health disorders. This has been stressed as a delivery system for the therapeutic fight against an array of pathophysiological situations. Actually, industry has applied this technology in the search for new oral delivery alternatives obtained upon the modification of the solubility properties of bioactive compounds. Significant works have been made in the last years for testing the input that nanomaterials and nanoparticles provide for an array of pathophysiological situations. In this frame, this review addresses general questions concerning the extent to which nanoparticles offer alternatives that improve therapeutic value, while avoid toxicity, by releasing bioactive compounds specifically to target tissues affected by specific chemical and pathophysiological settings. In this regard, to date, the contribution of nanoparticles to protect encapsulated bioactive compounds from degradation as a result of gastrointestinal digestion and cellular metabolism, to enable their release in a controlled manner, enhancing biodistribution of bioactive compounds, and to allow them to target those tissues affected by biological disturbances has been demonstrated.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available