Journal
PSYCHIATRY RESEARCH
Volume 251, Issue -, Pages 131-136Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.psychres.2016.12.041
Keywords
Schizophrenia; Chinese; Obesity; BMI; PANSS
Categories
Funding
- National Natural Science Foundation of China [81371477]
- Beijing Municipal Natural Science Foundation [7132063, 7072035]
- NARSAD Independent Investigator Grant [20314]
- Jiangsu Provincial Special Program of Medical Science - New Type Clinical Diagnosis and Treatment Project [BL2013018]
- Key Diagnosis and Treatment Program of Suzhou [LCZX201515, LCZX201316]
- Suzhou Key Medical Center for Psychiatric Diseases [Szzx201509]
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Obesity is a common comorbidity in schizophrenia. Few studies have addressed obesity in Chinese schizophrenia patients. The aims of this current study were to evaluate the prevalence, risk factors and clinical correlates of obesity in Chinese patients with schizophrenia. A total of 206 patients were recruited from a hospital in Beijing. Their clinical and anthropometric data together with plasma glucose and lipid parameters were collected. Positive and Negative Syndrome Scale (PANSS) was rated for all patients. Overall, 43 (20.9%) patients were obese and 67 (32.5%) were overweight. The obese patients had significantly higher glucose levels, triglyceride levels than non-obese patients. Females and patients with type 2 diabetes mellitus had increased risk for obesity. Correlation analysis showed that BMI was associated with sex, education levels, negative symptoms, total PANSS score, triglyceride levels and type 2 diabetes mellitus. Further stepwise regression analysis showed that sex, type 2 diabetes, education level, triglyceride and amount of smoking/day were significant predictors for obesity. Our study showed that the prevalence of obesity in Chinese patients with schizophrenia is higher than that in the general population. Some demographic and clinical variables are risk factors for obesity in schizophrenia.
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