4.3 Article

Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016)

Journal

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
Volume 86, Issue -, Pages 27-50

Publisher

WILEY
DOI: 10.1002/prot.25392

Keywords

CASP; NMR; protein structure prediction; X-ray crystallography

Funding

  1. US National Institute of General Medical Sciences (NIGMS/NIH) [GM100482]
  2. Latvian Council of Sciences [12.094]
  3. European Regional Development Fund [2010/0314/2DP/2.1.1.1.0/10/APIA/VIAA/052]
  4. Biostruct-X and the Latvian-French cooperation program Osmosis [7869]
  5. National Institutes of Health [GM102318, GM094585, GM115586]
  6. U. S. Department of Energy, Office of Biological and Environmental Research [DE-AC02-06CH11357]
  7. European Community's Seventh Framework Programme (FP7) [NMP3-SL-2008-213487]
  8. National Institutes of Health (NIH) [R01GM102810]
  9. Israel Science Foundation (ISF) [682/16]
  10. Wellcome Trust [097300/Z/11/Z, 106272/Z/14/Z]
  11. LISCB and Leicester-Wellcome Trust ISSF Fellowship at Leicester University
  12. Spanish Ministry of Economy, Industry and Competitiveness [BFU2014-53425-P]
  13. Fundacao para a Ciencia e a Tecnologia (Lisbon, Portugal) [PTDC/BIA-MIC/5947/2014, RECI/BBB-BEP/0124/2012, SFRH/BD/86821/2012]
  14. US National Institute of General Medical Sciences (NIGMS/NIH) [GM100482]
  15. Latvian Council of Sciences [12.094]
  16. European Regional Development Fund [2010/0314/2DP/2.1.1.1.0/10/APIA/VIAA/052]
  17. Biostruct-X and the Latvian-French cooperation program Osmosis [7869]
  18. National Institutes of Health [GM102318, GM094585, GM115586]
  19. U. S. Department of Energy, Office of Biological and Environmental Research [DE-AC02-06CH11357]
  20. European Community's Seventh Framework Programme (FP7) [NMP3-SL-2008-213487]
  21. National Institutes of Health (NIH) [R01GM102810]
  22. Israel Science Foundation (ISF) [682/16]
  23. Wellcome Trust [097300/Z/11/Z, 106272/Z/14/Z]
  24. LISCB and Leicester-Wellcome Trust ISSF Fellowship at Leicester University
  25. Spanish Ministry of Economy, Industry and Competitiveness [BFU2014-53425-P]
  26. Fundacao para a Ciencia e a Tecnologia (Lisbon, Portugal) [PTDC/BIA-MIC/5947/2014, RECI/BBB-BEP/0124/2012, SFRH/BD/86821/2012]
  27. Wellcome Trust [097300/Z/11/Z, 106272/Z/14/Z] Funding Source: Wellcome Trust
  28. Fundação para a Ciência e a Tecnologia [SFRH/BD/86821/2012, RECI/BBB-BEP/0124/2012, PTDC/BIA-MIC/5947/2014] Funding Source: FCT

Ask authors/readers for more resources

The functional and biological significance of the selected CASP12 targets are described by the authors of the structures. The crystallographers discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP12 experiment.

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