Related references
Note: Only part of the references are listed.Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana
Jiangtao Guo et al.
NATURE (2016)
Endolysosomal two-pore channels regulate autophagy in cardiomyocytes
Vanessa Garcia-Rua et al.
JOURNAL OF PHYSIOLOGY-LONDON (2016)
Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana
Alexander F. Kintzer et al.
NATURE (2016)
TPC2 controls pigmentation by regulating melanosome pH and size
Andrea L. Ambrosio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Expression of Ca2+-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells
Margarida Ruas et al.
EMBO JOURNAL (2015)
Two-pore Channels (TPC2s) and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) at Lysosomal-Sarcoplasmic Reticular Junctions Contribute to Acute and Chronic β-Adrenoceptor Signaling in the Heart
Rebecca A. Capel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic Cells
Abdelilah Arredouani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment
Yasuteru Sakurai et al.
SCIENCE (2015)
Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition
Leanne N. Hockey et al.
JOURNAL OF CELL SCIENCE (2015)
Convergent regulation of the lysosomal two-pore channel-2 by Mg2+, NAADP, PI(3,5) P2 and multiple protein kinases
Archana Jha et al.
EMBO JOURNAL (2014)
TPC1 Has Two Variant Isoforms, and Their Removal Has Different Effects on Endo-Lysosomal Functions Compared to Loss of TPC2
Margarida Ruas et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation
Yaping Lin-Moshier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Two-pore channels provide insight into the evolution of voltage-gated Ca2+ and Na+ channels
Taufiq Rahman et al.
SCIENCE SIGNALING (2014)
Reconstituted Human TPC1 Is a Proton-Permeable Ion Channel and Is Activated by NAADP or Ca2+
Samantha J. Pitt et al.
SCIENCE SIGNALING (2014)
High susceptibility to fatty liver disease in two-pore channel 2-deficient mice
Christian Grimm et al.
NATURE COMMUNICATIONS (2014)
mTOR Regulates Lysosomal ATP-Sensitive Two-Pore Na+ Channels to Adapt to Metabolic State
Chunlei Cang et al.
CELL (2013)
TPC Proteins Are Phosphoinositide-Activated Sodium-Selective Ion Channels in Endosomes and Lysosomes
Xiang Wang et al.
CELL (2012)
Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP
Patricia Gomez-Suaga et al.
HUMAN MOLECULAR GENETICS (2012)
Increased Expression of Fatty-Acid and Calcium Metabolism Genes in Failing Human Heart
Vanessa Garcia-Rua et al.
PLOS ONE (2012)
Transient Receptor Potential Mucolipin 1 (TRPML1) and Two-pore Channels Are Functionally Independent Organellar Ion Channels
Soichiro Yamaguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
A Novel Calcium Binding Site in the Slow Vacuolar Cation Channel TPC1 Senses Luminal Calcium Levels
Beata Dadacz-Narloch et al.
PLANT CELL (2011)
Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation
David B. Sauer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Purified TPC Isoforms Form NAADP Receptors with Distinct Roles for Ca2+ Signaling and Endolysosomal Trafficking
Margarida Ruas et al.
CURRENT BIOLOGY (2010)
An NAADP-gated Two-pore Channel Targeted to the Plasma Membrane Uncouples Triggering from Amplifying Ca2+ Signals
Eugen Brailoiu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
TPC2 Is a Novel NAADP-sensitive Ca2+ Release Channel, Operating as a Dual Sensor of Luminal pH and Ca2+
Samantha J. Pitt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Characterization of Two-pore Channel 2 (TPCN2)-mediated Ca2+ Currents in Isolated Lysosomes
Michael Schieder et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling
Eugen Brailoiu et al.
JOURNAL OF CELL BIOLOGY (2009)
NAADP mobilizes calcium from acidic organelles through two-pore channels
Peter J. Calcraft et al.
NATURE (2009)
The two-pore channel TPCN2 mediates NAADP-dependent Ca2+-release from lysosomal stores
Xiangang Zong et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2009)
Phaser crystallographic software
Airlie J. McCoy et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)
Metal-ligand geometry relevant to proteins and in proteins: sodium and potassium
MM Harding
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2002)
A putative two pore channel AtTPC1 mediates Ca2+ flux in Arabidopsis leaf cells
T Furuichi et al.
PLANT AND CELL PHYSIOLOGY (2001)
Molecular cloning of a novel form (two-repeat) protein related to voltage-gated sodium and calcium channels
K Ishibashi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)