Related references
Note: Only part of the references are listed.PPARγ signaling and metabolism: the good, the bad and the future
Maryam Ahmadian et al.
NATURE MEDICINE (2013)
Peroxisome Proliferator-Activated Receptor Targets for the Treatment of Metabolic Diseases
Francisco A. Monsalve et al.
MEDIATORS OF INFLAMMATION (2013)
Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ
Li Qiang et al.
CELL (2012)
Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding
Fernanda A. H. Batista et al.
PLOS ONE (2012)
PPARs: Fatty acid sensors controlling metabolism
Lars la Cour Poulsen et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2012)
Molecular basis for gene-specific transactivation by nuclear receptors
Mads M. Aagaard et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)
Discovery of isoindoline and tetrahydroisoquinoline derivatives as potent, selective PPAR delta agonists
Christopher A. Luckhurst et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator-Activated Receptor (PPAR) γ/δ Agonists with High Potency and in vivo Efficacy
Stefanie Keil et al.
CHEMMEDCHEM (2011)
The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2
Zhenji Gan et al.
GENES & DEVELOPMENT (2011)
Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation
Jang Hyun Choi et al.
NATURE (2011)
Endogenous Ligands for Nuclear Receptors: Digging Deeper
Michael Schupp et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5
Jang Hyun Choi et al.
NATURE (2010)
Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures
Takuji Oyama et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2009)
Identification of a PPARδ agonist with partial agonistic activity on PPARγ
Richard V. Connors et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Structural Insight into PPARγ Activation Through Covalent Modification with Endogenous Fatty Acids
Tsuyoshi Waku et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
C/EBP alpha and the Corepressors CtBP1 and CtBP2 Regulate Repression of Select Visceral White Adipose Genes during Induction of the Brown Phenotype in White Adipocytes by Peroxisome Proliferator-Activated Receptor gamma Agonists
Cecile Vernochet et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Fat and beyond: The diverse biology of PPAR gamma
Peter Tontonoz et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2008)
Rosiglitazone-associated fractures in type 2 diabetes - An analysis from a diabetes outcome progression trial (ADOPT)
Steven E. Kahn et al.
DIABETES CARE (2008)
Peroxisome proliferator-activated receptor structures: Ligand specificity, molecular switch and interactions with regulators
Vincent Zoete et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2007)
Substituted 2-[(4-aminomethyl)phenoxy]-2-methylpropionic acid PPARα agonists.: 1.: Discovery of a novel series of potent HDLc raising agents
Michael L. Sierra et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability
Frank H. Niesen et al.
NATURE PROTOCOLS (2007)
Crosstalk between peroxisome proliferator-activated receptor δ and VEGF stimulates cancer progression
Dingzhi Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
3,4,5-Trisubstituted isoxazoles as novel PPARδ agonists.: Part 2
Robert Epple et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Recombinant human PPAR-β/δ ligand-binding domain is locked in an activated conformation by endogenous fatty acids
SA Fyffe et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Cation-π interactions in protein-protein interfaces
PB Crowley et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2005)
Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-δ accelerates intestinal adenoma growth
RA Gupta et al.
NATURE MEDICINE (2004)
Thiazolidinedione use, fluid retention, and congestive heart failure
RW Nesto et al.
DIABETES CARE (2004)
Regulation of muscle fiber type and running endurance by PPARδ
YX Wang et al.
PLOS BIOLOGY (2004)
Activation of peroxisome proliferator-activated receptor δ stimulates the proliferation of human breast and prostate cancer cell lines
RL Stephen et al.
CANCER RESEARCH (2004)
Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle
WM He et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome
T Tanaka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The peroxisome proliferator-activated receptor β/δ agonist, GW501516, regulates the expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells
U Dressel et al.
MOLECULAR ENDOCRINOLOGY (2003)
Peroxisome-proliferator-activated receptor δ activates fat metabolism to prevent obesity
YX Wang et al.
CELL (2003)
The adipocyte in insulin resistance: key molecules and the impact of the thiazolidinediones
P Arner
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2003)
PPARγ is a very low-density lipoprotein sensor in macrophages
A Chawla et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα
HE Xu et al.
NATURE (2002)
Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors
HE Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport
WR Oliver et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Alteration of a single amino acid in peroxisome proliferator-activated receptor-α (PPARα) generates a PPARδ phenotype
I Takada et al.
MOLECULAR ENDOCRINOLOGY (2000)