Journal
CRITICAL REVIEWS IN BIOTECHNOLOGY
Volume 38, Issue 5, Pages 690-703Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/07388551.2017.1390728
Keywords
Bioproducts; metabolites; proteins; microbial biotechnology; microbial communication
Categories
Funding
- Biotechnology and Biological Sciences Research Council [BB/K020633/1] Funding Source: researchfish
- Engineering and Physical Sciences Research Council [1623367, EP/E036252/1] Funding Source: researchfish
- BBSRC [BB/K020633/1] Funding Source: UKRI
- EPSRC [EP/E036252/1] Funding Source: UKRI
Ask authors/readers for more resources
Monocultures have been the preferred production route in the bio-industry, where contamination has been a major bottleneck. In nature, microorganisms usually exist as part of organized communities and consortia, gaining benefits from co-habitation, keeping invaders at bay. There is increasing interest in the use of co-cultures to tackle contamination issues, and simultaneously increase productivity and product diversity. The feasibility of extending the natural phenomenon of co-habitation to the biomanufacturing industry in the form of co-cultures requires careful and systematic consideration of several aspects. This article will critically examine and review current work on microbial co-cultures, with the intent of examining the concept and proposing a design pipeline that can be developed in a biomanufacturing context.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available