Journal
MATERIALS TODAY COMMUNICATIONS
Volume 15, Issue -, Pages 128-133Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.mtcomm.2018.03.003
Keywords
Collagen; Multiwalled carbon nanotubes; Functionalization; Cross linking; Hemostasis; Hydrophylicity
Categories
Funding
- Tai Mountain Scholar project from We Go group Co., Ltd
- Shandong province government of China
- Chang Jiang Scholars Program
- National Natural Science Foundation of China [51073047, 91016015]
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Collagen (COL) is a biopolymer that widely used for a number of medical treatments especially haemostatic applications. To enhance the medical performance of COL and explore an alternative approach, its modification using Carbon Nanotubes is considered. To treat a valuable cross linking and chemical bonding, aminated MWCNTs (MWCNT-NH2)s, which introduced the aromatic amine on the side wall of MWCNTs, were jointed to the COL sponges (COLSP)s. To explore the origin of this behaviour, dispersion of MWCNT-NH(2)s on COLSPs and their interfacial interactions were investigated by SEM, FT-IR and XPS. The analytical results show a relatively strong interaction existed between aminated MWCNTs and the sidewall of COLSPs. The hydrophilicity test results revealed significant increment in water uptake of MWCNT-NH(2)s/COL composites with increasing the concentration of MWCNT-NH(2)s until 13 wt%. Additionally, the addition of aminated MWCNTs decreases the coagulation time of anti coagulated rabbit blood, indicating that the MWCNT-NH(2)s/COLSPs have significant procoagulant activity. Due to agglomeration of MWCNT-NH(2)s in solution, also, the surface limitation of sponges, increment in concentration of MWCNT-NH(2)s up to 14 wt% is not adequate. This study promises that the MWCNT-NH(2)s cross-linked COL fibres present mechanical strength significantly higher than that of neat COL fibres.
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