Journal
ARRHYTHMIA & ELECTROPHYSIOLOGY REVIEW
Volume 7, Issue 2, Pages 103-110Publisher
RADCLIFFE CARDIOLOGY
DOI: 10.15420/aer.2018.6.2
Keywords
His bundle; pacing therapy; heart failure; left bundle branch block reversal; bradycardia pacing; atrial fibrillation
Categories
Funding
- British Heart Foundation [FS/13/44/30291, FS/15/53/31615, CS/15/3/31405] Funding Source: Medline
Ask authors/readers for more resources
Biventricular pacing has revolutionised the treatment of heart failure in patients with sinus rhythm and left bundle branch block; however, left ventricular-lead placement is not always technically possible. Furthermore, biventricular pacing does not fully normalise ventricular activation and, therefore, the ventricular resynchronisation is imperfect. Right ventricular pacing for bradycardia may cause or worsen heart failure in some patients by causing dyssynchronous ventricular activation. His bundle pacing activates the ventricles via the native His-Purkinje system, resulting in true physiological pacing, and, therefore, is a promising alternate site for pacing in bradycardia and traditional CRT indications in cases where it can overcome left bundle branch block. Furthermore, it may open up new indications for pacing therapy in heart failure, such as targeting patients with PR prolongation, but a narrow QRS duration. In this article we explore the physiology, technology and potential roles of His bundle pacing in the prevention and treatment of heart failure.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available