Related references
Note: Only part of the references are listed.Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index
Alice E. Kane et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2016)
Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs
Ha-Neui Kim et al.
MOLECULAR ENDOCRINOLOGY (2015)
The Sirt1 Activators SRT2183 and SRT3025 Inhibit RANKL-Induced Osteoclastogenesis in Bone Marrow-Derived Macrophages and Down-Regulate Sirt3 in Sirt1 Null Cells
Irina Gurt et al.
PLOS ONE (2015)
SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass
Evi M. Mercken et al.
AGING CELL (2014)
The Sirtuin1 Activator SRT3025 Down-Regulates Sclerostin and Rescues Ovariectomy-Induced Bone Loss and Biomechanical Deterioration in Female Mice
Hanna Artsi et al.
ENDOCRINOLOGY (2014)
Sirtuin1 (Sirt1) Promotes Cortical Bone Formation by Preventing β-Catenin Sequestration by FoxO Transcription Factors in Osteoblast Progenitors
Srividhya Iyer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Resveratrol supplementation preserves long bone mass, microstructure, and strength in hindlimb-suspended old male rats
Stephanie M. Durbin et al.
JOURNAL OF BONE AND MINERAL METABOLISM (2014)
Resveratrol Increases Bone Mineral Density and Bone Alkaline Phosphatase in Obese Men: A Randomized Placebo-Controlled Trial
Marie Juul Ornstrup et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)
The SIRT1 Activator SRT1720 Extends Lifespan and Improves Health of Mice Fed a Standard Diet
Sarah J. Mitchell et al.
CELL REPORTS (2014)
Sirt1 Extends Life Span and Delays Aging in Mice through the Regulation of Nk2 Homeobox 1 in the DMH and LH
Akiko Satoh et al.
CELL METABOLISM (2013)
SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin
Petra Simic et al.
EMBO MOLECULAR MEDICINE (2013)
Silent information regulator (Sir)T1 inhibits NF-B signaling to maintain normal skeletal remodeling
James R. Edwards et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2013)
A Dietary Regimen of Caloric Restriction or Pharmacological Activation of SIRT1 to Delay the Onset of Neurodegeneration
Johannes Graeff et al.
JOURNAL OF NEUROSCIENCE (2013)
Resveratrol Mediated Modulation of Sirt-1/Runx2 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells: Potential Role of Runx2 Deacetylation
Mehdi Shakibaei et al.
PLOS ONE (2012)
Sirt1 Is a Regulator of Bone Mass and a Repressor of Sost Encoding for Sclerostin, a Bone Formation Inhibitor
Einav Cohen-Kfir et al.
ENDOCRINOLOGY (2011)
Resveratrol Promotes Osteogenesis of Human Mesenchymal Stem Cells by Upregulating RUNX2 Gene Expression via the SIRT1/FOXO3A Axis
Pei-Chi Tseng et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2011)
TIEG1/KLF10 Modulates Runx2 Expression and Activity in Osteoblasts
John R. Hawse et al.
PLOS ONE (2011)
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
Daniel Herranz et al.
NATURE COMMUNICATIONS (2010)
Co-stimulation of the Bone-related Runx2 P1 Promoter in Mesenchymal Cells by SP1 and ETS Transcription Factors at Polymorphic Purine-rich DNA Sequences (Y-repeats)
Ying Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Transcription factors controlling osteoblastogenesis
Pierre J. Marie
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2008)
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
Kevin J. Pearson et al.
CELL METABOLISM (2008)
SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice
Alexander S. Banks et al.
CELL METABOLISM (2008)
BMP2 Regulates Osterix through Msx2 and Runx2 during Osteoblast Differentiation
Takuma Matsubara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice
Jamie L. Barger et al.
PLOS ONE (2008)
SIRT1 transgenic mice show phenotypes resembling calorie restriction
Laura Bordone et al.
AGING CELL (2007)
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
Jill C. Milne et al.
NATURE (2007)
Dlx5 drives Runx2 expression and osteogenic differentiation in developing cranial suture inesenchyme
Nicolas Holleville et al.
DEVELOPMENTAL BIOLOGY (2007)
BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network
Mohammad Q. Hassan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α
Marie Lagouge et al.
CELL (2006)
Resveratrol improves health and survival of mice on a high-calorie diet
Joseph A. Baur et al.
NATURE (2006)
Mammalian sirtuins - emerging roles in physiology, aging, and calorie restriction
Marcia C. Haigis et al.
GENES & DEVELOPMENT (2006)
Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells
CM Bäckesjö et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2006)
Bone morphogenetic protein-2 stimulates Runx2 acetylation
Eun-Joo Jeon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Runx2-mediated regulation of the zinc finger Osterix/Sp7 gene
Yasuhiko Nishio et al.
GENE (2006)
Repression of Runx2 function by TGF-β through recruitment of class II histone deacetylases by Smad3
JS Kang et al.
EMBO JOURNAL (2005)
Distinct effects of PPARγ insufficiency on bone marrow cells, osteoblasts, and osteoclastic cells
H Kawaguchi et al.
JOURNAL OF BONE AND MINERAL METABOLISM (2005)
Dlx3 transcriptional regulation of osteoblast differentiation: Temporal recruitment of Msx2 Dlx3 an Dlx5 homeodomain proteins to chromatin of the osteocalcin gene
MQ Hassan et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma
DM Thomas et al.
JOURNAL OF CELL BIOLOGY (2004)
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
F Picard et al.
NATURE (2004)
Histone deacetylase 3 interacts with Runx2 to repress the osteocalcin promoter and regulate osteoblast differentiation
TM Schroeder et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Activation of peroxisome proliferator-activated receptor-γ inhibits the Runx2-mediated transcription of osteocalcin in osteoblasts
MJ Jeon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Control of osteoblast function and regulation of bone mass
S Harada et al.
NATURE (2003)
The novel zinc finger-containing transcription factor Osterix is required for osteoblast differentiation and bone formation
K Nakashima et al.
CELL (2002)
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
S Imai et al.
NATURE (2000)
Therapeutic approaches to bone diseases
GA Rodan et al.
SCIENCE (2000)