Journal
PHYTOCHEMISTRY LETTERS
Volume 19, Issue -, Pages 266-270Publisher
ELSEVIER
DOI: 10.1016/j.phytol.2017.02.006
Keywords
Alkaloid; Endophytic fungus; Stagonosporopsis oculihominis; Cytotoxicity
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Funding
- Natural Science Key Research Program of Anhui Province University [KJ2016A856]
- Key Disciplines Program of State Administration of Traditional Chinese Medicines of China
- Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, CAS [AB2015001]
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Two new alkaloids (1-2), together with six known compounds (3-8), were isolated from cultures of the endophytic fungus Stagonosporopsis oculihominis. Their structures were elucidated through extensive spectroscopic methods including 2D NMR and HRMS analyses. The absolute configurations of 1 was determined by the comparison of experimental and theoretical electronic circular dichroism spectra. The new compounds were investigated for their cytotoxicity against five human cancer cell lines. (C) 2017 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.
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