4.3 Article

Four new limonoids from the seeds of Chukrasia tabularis A. Juss.

Journal

PHYTOCHEMISTRY LETTERS
Volume 19, Issue -, Pages 12-17

Publisher

ELSEVIER
DOI: 10.1016/j.phytol.2016.11.004

Keywords

Chukrasia tabularis; Limonoids; Phragmalin; Mexicanolide; ECD exciton chirality method

Funding

  1. National Natural Sciences Foundation of China [81573550]
  2. Youth Fund Project of Basic Research Program of Jiangsu Province (Natural Science Foundation) [BK20160077]
  3. Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
  4. Ph. D. Programs Foundation of Ministry of Education of China [20120096130002]

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Two new C-15 enolic acyl phragmalin- type limonoid orthoesters (1-2) which possessed a C-15-propionyl phragmalin skeleton and two new mexicanolide-type limonoids (3-4) were isolated from the ethanol extract of seeds of Chukrasia tabularis A. Juss. Their structures were established on the basis of spectroscopic analyses and electronic circular dichroism (ECD) exciton chirality method. Additionally, all of the compounds were screened against three human tumor cell lines MCF-7, SMMC-7721, and U2OS. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.

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