Journal
PHYTOCHEMISTRY
Volume 143, Issue -, Pages 36-44Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2017.07.008
Keywords
Kaempferia roscoeana; Zingiberaceae; Roscotanes A-D; Roscoranes A-D; Abietane; Pimarane; Antimalarial activity; Antimicrobial activity
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Funding
- Center of Excellence for Environment Health and Toxicology, (EHT-PERDO)
- Ministry of Education
- Chulabhorn Research Center
- Institute of Molecular Biosciences, Mahidol University
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Eight previously undescribed ditepenoids, including four oxygenated abietanes (roscotanes A-D) and four oxygenated pimaranes (roscoranes A-D), along with twelve known diterpenoids were isolated from the whole plants of Kaempferia roscoeana. Their structures were elucidated by extensive spectroscopic analysis, and the structure of roscotane A was further confirmed by single crystal X-ray diffraction analysis. Most isolated compounds were evaluated for their antimicrobial and antimalarial activities. (C) 2017 Elsevier Ltd. All rights reserved.
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