4.1 Article

Oxidative Route to Pyrroloisoquinoline-2,3-dione

Journal

ARKIVOC
Volume -, Issue -, Pages 184-190

Publisher

ARKAT USA INC
DOI: 10.24820/ark.5550190.p010.433

Keywords

Isoquinoline; pyrrole; aerobic oxidation; synthesis; green chemistry; dione

Funding

  1. Science & Engineering Research Board (SERB), Department of Science & Technology, New Delhi

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We herein report an efficient constructive method for synthesis of structurally important Pyrroloisoquinoline-2,3-dione from dihydroisoquinoline through oxidative cyclisation. Process is optimised to give best efficiency at gram scale and laborious purification techniques such as column chromatography or recrystallisation were avoided in all steps further featuring uniqueness of this method as compared to the available literature. [GRAPHICS] .

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