Journal
PHYSIOLOGY
Volume 32, Issue 5, Pages 357-366Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00030.2016
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Funding
- American Heart Association [0830239N, 12SDG8980032]
- Endocrine Fellows Foundation Endocrine Research Grant
- National Institutes of Health [R21 DK-113500, R01 HL-66072, P01 HL-51971, P20 GM-121334]
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Polycystic ovary syndrome (PCOS) is the most common endocrine disorder that affects reproductive-age women. Hyperandrogenemia is present in a significant fraction(similar to 80%) of women with PCOS. Increased prevalence of cardiometabolic risk factors is frequently observed in PCOS women. The present review aims to highlight the key role of androgens in mediating the negative cardiometabolic profile observed in PCOS women.
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