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Sex-Specific Effects of Estrogen and Androgen on Gene Expression in Human Monocyte-Derived Osteoclasts
Jun Wang et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2011)
Cortical Consolidation due to Increased Mineralization and Endosteal Contraction in Young Adult Men: A Five-Year Longitudinal Study
Claes Ohlsson et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
Higher Serum Free Testosterone Concentration in Older Women Is Associated with Greater Bone Mineral Density, Lean Body Mass, and Total Fat Mass: The Cardiovascular Health Study
Chevon M. Rariy et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
Reference Ranges for Testosterone in Men Generated Using Liquid Chromatography Tandem Mass Spectrometry in a Community-Based Sample of Healthy Nonobese Young Men in the Framingham Heart Study and Applied to Three Geographically Distinct Cohorts
Shalender Bhasin et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
Biphasic and Dosage-Dependent Regulation of Osteoclastogenesis by β-Catenin
Wei Wei et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
GATA4 Regulates Estrogen Receptor-α-Mediated Osteoblast Transcription
Gustavo A. Miranda-Carboni et al.
MOLECULAR ENDOCRINOLOGY (2011)
Matrix-embedded cells control osteoclast formation
Jinhu Xiong et al.
NATURE MEDICINE (2011)
Evidence for osteocyte regulation of bone homeostasis through RANKL expression
Tomoki Nakashima et al.
NATURE MEDICINE (2011)
Growth Hormone plus Childhood Low-Dose Estrogen in Turner's Syndrome
Judith L. Ross et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Influence of age and sex steroids on bone density and geometry in middle-aged and elderly European men
K. A. Ward et al.
OSTEOPOROSIS INTERNATIONAL (2011)
Pubertal timing and body mass index gain from birth to maturity in relation with femoral neck BMD and distal tibia microstructure in healthy female subjects
T. Chevalley et al.
OSTEOPOROSIS INTERNATIONAL (2011)
Daidzein Prevents the Increase in CD4+CD28null T Cells and B Lymphopoesis in Ovariectomized Mice: A Key Mechanism for Anti-Osteoclastogenic Effect
Abdul Malik Tyagi et al.
PLOS ONE (2011)
Remodeling of Actin Cytoskeleton in Mouse Periosteal Cells under Mechanical Loading Induces Periosteal Cell Proliferation during Bone Formation
Daisuke Sakai et al.
PLOS ONE (2011)
Overexpression of Bcl2 in Osteoblasts Inhibits Osteoblast Differentiation and Induces Osteocyte Apoptosis
Takeshi Moriishi et al.
PLOS ONE (2011)
Ovariectomy disregulates osteoblast and osteoclast formation through the T-cell receptor CD40 ligand
Jau-Yi Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Roles of transactivating functions 1 and 2 of estrogen receptor-α in bone
A. E. Borjesson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial
James T. Dalton et al.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2011)
Effect of oxandrolone and timing of pubertal induction on final height in Turner's syndrome: randomised, double blind, placebo controlled trial
Emma Jane Gault et al.
BMJ-BRITISH MEDICAL JOURNAL (2011)
Decreased oxidative stress and greater bone anabolism in the aged, when compared to the young, murine skeleton with parathyroid hormone administration
Robert L. Jilka et al.
AGING CELL (2010)
Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice
Robert S. Weinstein et al.
AGING CELL (2010)
Increased Number of Sex Chromosomes Affects Height in a Nonlinear Fashion: A Study of 305 Patients With Sex Chromosome Aneuploidy
Anne Marie Ottesen et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2010)
Long-Term Effects of Dihydrotestosterone Treatment on Prostate Growth in Healthy, Middle-Aged Men Without Prostate Disease A Randomized, Placebo-Controlled Trial
Amanda Idan et al.
ANNALS OF INTERNAL MEDICINE (2010)
Meta-analysis: Excess Mortality After Hip Fracture Among Older Women and Men
Patrick Haentjens et al.
ANNALS OF INTERNAL MEDICINE (2010)
How B cells influence bone biology in health and disease
Mark C. Horowitz et al.
BONE (2010)
Peak bone mineral density, lean body mass and fractures
Annemieke M. Boot et al.
BONE (2010)
Osteocyte apoptosis and control of bone resorption following ovariectomy in mice
K. B. Emerton et al.
BONE (2010)
Update of the National Surgical Adjuvant Breast and Bowel Project Study of Tamoxifen and Raloxifene (STAR) P-2 Trial: Preventing Breast Cancer
Victor G. Vogel et al.
CANCER PREVENTION RESEARCH (2010)
FoxO-Mediated Defense against Oxidative Stress in Osteloblasts, Is Indispensable for Skeletal Homeostasis in Mice
Elena Ambrogini et al.
CELL METABOLISM (2010)
From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis
Stavros C. Manolagas
ENDOCRINE REVIEWS (2010)
A Double-Blind, Placebo-Controlled Comparison of Letrozole to Oxandrolone Effects upon Growth and Puberty of Children with Constitutional Delay of Puberty and Idiopathic Short Stature
Shadab Salehpour et al.
HORMONE RESEARCH IN PAEDIATRICS (2010)
Augmentation of cortical bone mineral density in women with polycystic ovary syndrome: a peripheral quantitative computed tomography (pQCT) study
D. Kassanos et al.
HUMAN REPRODUCTION (2010)
Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor α-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF, Leading to Phosphatidylinositol 3-Kinase/AKT-dependent Wnt/LRP5 Receptor-independent Activation of β-Catenin Signaling
Andrew Sunters et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Discovery of the Selective Androgen Receptor Modulator MK-0773 Using a Rational Development Strategy Based on Differential Transcriptional Requirements for Androgenic Anabolism Versus Reproductive Physiology
Azriel Schmidt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Direct transformation from quiescence to bone formation in the adult periosteum following a single brief period of bone loading
Matthew J. Pead et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Effect of ovariectomy on bone response to in vivo external loading
Hiroshi Hagino et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Androgen Receptor Disruption Increases the Osteogenic Response to Mechanical Loading in Male Mice
Filip Callewaert et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Early induction of alterations in cancellous and cortical bone histology after orchiectomy in mature rats
M. Gunness et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Relations between histologic indices of bone formation: Implications for the pathogenesis of spinal osteoporosis
A.M. Parfitt et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Theoretical perspective: A new model for the regulation of bone resorption, with particular reference to the effects of bisphosphonates
A.M. Parfitt et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Growth Hormone Protects Against Ovariectomy-Induced Bone Loss in States of Low Circulating Insulin-like Growth Factor (IGF-1)
J. Christopher Fritton et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Bone mineral loss and recovery after 17 weeks of bed rest
Adrian D. Leblanc et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Peak Bone Mass From Longitudinal Data: Implications for the Prevalence, Pathophysiology, and Diagnosis of Osteoporosis
Claudie Berger et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
The Role of Estrogen Receptor α in Growth Plate Cartilage for Longitudinal Bone Growth
Anna E. Borjesson et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
A Longitudinal HR-pQCT Study of Alendronate Treatment in Postmenopausal Women With Low Bone Density: Relations Among Density, Cortical and Trabecular Microarchitecture, Biomechanics, and Bone Turnover
Andrew J. Burghardt et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Rapid Growth Produces Transient Cortical Weakness: A Risk Factor for Metaphyseal Fractures During Puberty
Qingju Wang et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Sexual Dimorphism in Cortical Bone Size and Strength But Not Density Is Determined by Independent and Time-Specific Actions of Sex Steroids and IGF-1: Evidence From Pubertal Mouse Models
Filip Callewaert et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Tall Stature without Growth Hormone: Four Male Patients with Aromatase Deficiency
Vincenzo Rochira et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
Sex Steroid Hormones in Older Men: Longitudinal Associations with 4.5-Year Change in Hip Bone Mineral Density-The Osteoporotic Fractures in Men Study
Jane A. Cauley et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
Structural Decay of Bone Microarchitecture in Men with Prostate Cancer Treated with Androgen Deprivation Therapy
E. J. Hamilton et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
Update on Estrogens and the Skeleton
Sundeep Khosla
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
Frailty, Serum Androgens, and the CAG Repeat Polymorphism: Results from the Massachusetts Male Aging Study
Thomas G. Travison et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
Non-nuclear estrogen receptor α signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice
Ken L. Chambliss et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Skeletal sexual dimorphism: relative contribution of sex steroids, GH-IGF1, and mechanical loading
Filip Callewaert et al.
JOURNAL OF ENDOCRINOLOGY (2010)
Toremifene to Reduce Fracture Risk in Men Receiving Androgen Deprivation Therapy for Prostate Cancer
Matthew R. Smith et al.
JOURNAL OF UROLOGY (2010)
Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study
Roger M. D. Zebaze et al.
LANCET (2010)
Research Resource: The Androgen Receptor Modulates Expression of Genes with Critical Roles in Muscle Development and Function
Anastasia Wyce et al.
MOLECULAR ENDOCRINOLOGY (2010)
The Estrogen Receptor-α in Osteoclasts Mediates the Protective Effects of Estrogens on Cancellous But Not Cortical Bone
Marta Martin-Millan et al.
MOLECULAR ENDOCRINOLOGY (2010)
Adverse Events Associated with Testosterone Administration
Shehzad Basaria et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Lasofoxifene in Postmenopausal Women with Osteoporosis
Steven R. Cummings et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Identification of Late-Onset Hypogonadism in Middle-Aged and Elderly Men
Frederick C. W. Wu et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Gonadal sex steroid status and bone health in middle-aged and elderly European men
D. Vanderschueren et al.
OSTEOPOROSIS INTERNATIONAL (2010)
Baseline serum estradiol and fracture reduction during treatment with hormone therapy: The Women's Health Initiative randomized trial
J. A. Cauley et al.
OSTEOPOROSIS INTERNATIONAL (2010)
Sex hormones and their receptors in bone homeostasis: insights from genetically modified mouse models
L. Vico et al.
OSTEOPOROSIS INTERNATIONAL (2010)
Estrogen Actions in the Brain and the Basis for Differential Action in Men and Women: A Case for Sex-Specific Medicines
Glenda E. Gillies et al.
PHARMACOLOGICAL REVIEWS (2010)
Pituitary growth hormone network responses are sexually dimorphic and regulated by gonadal steroids in adulthood
Claudia Sanchez-Cardenas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
What old means to bone
Stavros C. Manolagas et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2010)
Estrogen receptor-α and -β and aromatase knockout effects on lower limb muscle mass and contractile function in female mice
Marybeth Brown et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
References for growth and pubertal development from birth to 21 years in Flanders, Belgium
M. Roelants et al.
ANNALS OF HUMAN BIOLOGY (2009)
Physical activity in the androgen receptor knockout mouse: Evidence for reversal of androgen deficiency on cancellous bone
Jill Ophoff et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Long-term changes in bone mineral density and predicted fracture risk in patients receiving androgen-deprivation therapy for prostate cancer, with stratification of treatment based on presenting values
Vivek K. Wadhwa et al.
BJU INTERNATIONAL (2009)
Estrogen-specific action on bone geometry and volumetric bone density: Longitudinal observations in an adult with complete androgen insensitivity
Youri Taes et al.
BONE (2009)
Increased RANK ligand in bone marrow of orchiectomized rats and prevention of their bone loss by the RANK ligand inhibitor osteoprotegerin
Xiaodong Li et al.
BONE (2009)
New selective estrogen and androgen receptor modulators
Bart L. Clarke et al.
CURRENT OPINION IN RHEUMATOLOGY (2009)
Androgen Signaling in Myocytes Contributes to the Maintenance of Muscle Mass and Fiber Type Regulation But Not to Muscle Strength or Fatigue
Jill Ophoff et al.
ENDOCRINOLOGY (2009)
Short-term aromatase inhibition: effects on glucose metabolism and serum leptin levels in young and elderly men
B. Lapauw et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2009)
Correlates of increased lean muscle mass in women with polycystic ovary syndrome
E. Carmina et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2009)
Differential regulation of bone and body composition in male mice with combined inactivation of androgen and estrogen receptor-α
Filip Callewaert et al.
FASEB JOURNAL (2009)
Increased Lipid Oxidation Causes Oxidative Stress, Increased Peroxisome Proliferator-activated Receptor-γ Expression, and Diminished Pro-osteogenic Wnt Signaling in the Skeleton
Maria Almeida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Deleterious Effect of Late Menarche on Distal Tibia Microstructure in Healthy 20-Year-Old and Premenopausal Middle-Aged Women
Thierry Chevalley et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2009)
Elevated Aromatase Expression in Osteoblasts Leads to Increased Bone Mass Without Systemic Adverse Effects
Klara Sjogren et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2009)
Mineralization and Bone Resorption Are Regulated by the Androgen Receptor in Male Mice
Cherie Chiang et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2009)
Bone Structure at the Distal Radius During Adolescent Growth
Salman Kirmani et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2009)
The Age of Puberty Determines Sexual Dimorphism in Bone Structure: A Male/Female Co-Twin Control Study
Sandra Iuliano-Burns et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Anthropometric and Skeletal Phenotype in Men with Idiopathic Osteoporosis and Their Sons Is Consistent with Deficient Estrogen Action during Maturation
Bruno Lapauw et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Aromatase and 5α-Reductase Inhibition during an Exogenous Testosterone Clamp Unveils Selective Sex Steroid Modulation of Somatostatin and Growth Hormone Secretagogue Actions in Healthy Older Men
Johannes D. Veldhuis et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
The Effects of Serum Testosterone, Estradiol, and Sex Hormone Binding Globulin Levels on Fracture Risk in Older Men
Erin S. LeBlanc et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Effects of Aromatase Inhibition on Bone Mineral Density and Bone Turnover in Older Men with Low Testosterone Levels
Sherri-Ann M. Burnett-Bowie et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Increased Estrogen Rather Than Decreased Androgen Action Is Associated with Longer Androgen Receptor CAG Repeats
Ilpo T. Huhtaniemi et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Nonsteroidal Selective Androgen Receptor Modulators (SARMs): Dissociating the Anabolic and Androgenic Activities of the Androgen Receptor for Therapeutic Benefit
Michael L. Mohler et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Conditional Inactivation of Androgen Receptor Gene in the Nervous System: Effects on Male Behavioral and Neuroendocrine Responses
Kalina Raskin et al.
JOURNAL OF NEUROSCIENCE (2009)
Susceptibility to Autoimmunity and B Cell Resistance to Apoptosis in Mice Lacking Androgen Receptor in B Cells
Saleh Altuwaijri et al.
MOLECULAR ENDOCRINOLOGY (2009)
Coordination of PGC-1 beta and iron uptake in mitochondrial biogenesis and osteoclast activation
Kiyo-aki Ishii et al.
NATURE MEDICINE (2009)
Aromatase deficiency in men: a clinical perspective
Vincenzo Rochira et al.
NATURE REVIEWS ENDOCRINOLOGY (2009)
Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis
Steven R. Cummings et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Lumbar spine peak bone mass and bone turnover in men and women: a longitudinal study
J. S. Walsh et al.
OSTEOPOROSIS INTERNATIONAL (2009)
Remaining lifetime and absolute 10-year probabilities of osteoporotic fracture in Swiss men and women
K. Lippuner et al.
OSTEOPOROSIS INTERNATIONAL (2009)
Bone micro-architecture and determinants of strength in the radius and tibia: age-related changes in a population-based study of normal adults measured with high-resolution pQCT
N. Dalzell et al.
OSTEOPOROSIS INTERNATIONAL (2009)
Prepubertal OVX increases IGF-I expression and bone accretion in C57BL/6J mice
Kristen E. Govoni et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Endogenous sex hormones and incident fracture risk in older men - The Dubbo Osteoporosis Epidemiology Study
Christian Meier et al.
ARCHIVES OF INTERNAL MEDICINE (2008)
A novel mutation in the human aromatase gene: Insights on the relationship among serum estradiol, longitudinal growth and bone mineral density in an adult man under estrogen replacement treatment
Fabio Lanfranco et al.
BONE (2008)
Targeting of androgen receptor in bone reveals a lack of androgen anabolic action and inhibition of osteogenesis - A model for compartment-specific androgen action in the skeleton
Kristine M. Wiren et al.
BONE (2008)
Sex steroids and bone turnover markers in men with symptomatic vertebral fractures
S. P. Tuck et al.
BONE (2008)
Osteocytes, mechanosensing and Wnt signaling
Lynda F. Bonewald et al.
BONE (2008)
Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival
Susan A. Krum et al.
EMBO JOURNAL (2008)
Tissue selectivity of the anabolic steroid, 19-nor-4-androstenediol-3β,17β-diol in male Sprague Dawley rats:: Selective stimulation of muscle mass and bone mineral density relative to prostate mass
Stephanie T. Page et al.
ENDOCRINOLOGY (2008)
Comparison of bone mineral density and body proportions between women with complete androgen insensitivity syndrome and women with gonadal dysgenesis
T. S. Han et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2008)
Redox-based regulation of signal transduction: Principles, pitfalls, and promises
Yvonne M. W. Janssen-Heininger et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Association between 5-α reductase inhibition and risk of hip fracture
Steven J. Jacobsen et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2008)
Effect of testosterone supplementation on functional mobility, cognition, and other parameters in older men - A randomized controlled trial
Marielle H. Emmelot-Vonk et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2008)
Older men with low serum estradiol and high serum SHBG have an increased risk of fractures
Dan Mellstroem et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2008)
Efficacy of Bazedoxifene in Reducing New Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis: Results From a 3-Year, Randomized, Placebo-, and Active-Controlled Clinical Trial
Stuart L. Silverman et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2008)
Bone mass is preserved and cancellous architecture altered due to cyclic loading of the mouse tibia after orchidectomy
J. Christopher Fritton et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2008)
ERα and AP-1 interact in vivo with a specific sequence of the F promoter of the human ERα gene in osteoblasts
Elisabetta Lambertini et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Pharmacodynamics of growth hormone abuse biomarkers and the influence of gender and testosterone: A randomized double-blind placebo-controlled study in young recreational athletes
Anne E. Nelson et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Correlations between serum testosterone, estradiol, and sex hormone-binding globulin and bone mineral density in a diverse sample of men
Andre B. Araujo et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Associations of serum sex hormone-binding globulin and sex hormone concentrations with hip fracture risk in postmenopausal women
Jennifer S. Lee et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Consensus Statement on the Diagnosis and Treatment of Children with Idiopathic Short Stature: A Summary of the Growth Hormone Research Society, the Lawson Wilkins Pediatric Endocrine Society, and the European Society for Paediatric Endocrinology Workshop
P. Cohen et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Impact on bone of an estrogen receptor-α gene loss of function mutation
Eric P. Smith et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
In vivo characterization of estrogen receptor modulators with reduced genomic versus nongenomic activity in vitro
Christiane Otto et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2008)
The effect of 5α-reductase inhibition with dutasteride and finasteride on bone mineral density, serum lipoproteins, hemoglobin, prostate specific antigen and sexual function in healthy young men
John K. Amory et al.
JOURNAL OF UROLOGY (2008)
Estrogen receptor β isoform-specific induction of transforming growth factor β-inducible early gene-1 in human osteoblast cells:: An essential role for the activation function 1 domain
John R. Hawse et al.
MOLECULAR ENDOCRINOLOGY (2008)
Transcriptome profiling of estrogen-regulated genes in human primary osteoblasts reveals an osteoblast-specific regulation of the insulin-like growth factor binding protein 4 gene
Stefanie Denger et al.
MOLECULAR ENDOCRINOLOGY (2008)
Unique ERα Cistromes Control Cell Type-Specific Gene Regulation
Susan A. Krum et al.
MOLECULAR ENDOCRINOLOGY (2008)
Longitudinal changes in BMD and bone geometry in a population-based study
Fulvio Lauretani et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2008)
Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin
Alexander G. Robling et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Estradiol rapidly inhibits osteoclastogenesis and RANKL expression in bone marrow cultures in postmenopausal women: a pilot study
P. Taxel et al.
OSTEOPOROSIS INTERNATIONAL (2008)
A population-based assessment of rates of bone loss at multiple skeletal sites: Evidence for substantial trabecular bone loss in young adult women and men
B. Lawrence Riggs et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2008)
Abnormalities of the axial and proximal appendicular skeleton in adults with Laron syndrome (growth hormone insensitivity)
L. Kornreich et al.
SKELETAL RADIOLOGY (2008)
Androgen receptor (AR) coregulators: A diversity of functions converging on and regulating the AR transcriptional complex
Hannelore V. Heemers et al.
ENDOCRINE REVIEWS (2007)
Extranuclear steroid receptors: Nature and actions
Stephen R. Hammes et al.
ENDOCRINE REVIEWS (2007)
Gone with the Wnts:: β-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism
Stavros C. Manolagas et al.
MOLECULAR ENDOCRINOLOGY (2007)
Substituted 6-(1-Pyrrolidine)quinolin-2(1H)-ones as novel selective androgen receptor modulators
Esther Martinborough et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
ROS as signalling molecules:: mechanisms that generate specificity in ROS homeostasis
Benoit D'Autreaux et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids
Maria Almeida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting β-catenin from T cell factor- to Forkhead box O-mediated transcription
Maria Almeida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Low bone mineral density and fracture burden in postmenopausal women
Ann Cranney et al.
CANADIAN MEDICAL ASSOCIATION JOURNAL (2007)
Estrogen prevents bone loss via estrogen receptor α and induction of Fas ligand in osteoclasts
Takashi Nakamura et al.
CELL (2007)
A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction
J. Ignacio Aguirre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The skeletal responsiveness to mechanical loading is enhanced in mice with a null mutation in estrogen receptor-β
L. K. Saxon et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
The association of sex hormone levels with quantitative ultrasound, bone mineral density, bone turnover and osteoporotic fractures in older men and women
Natalia O. Kuchuk et al.
CLINICAL ENDOCRINOLOGY (2007)
Wnt/β-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor α
Victoria J. Armstrong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Skeletal effects of long-term estrogen and testosterone replacement treatment in a man with congenital aromatase deficiency: Evidences of a priming effect of estrogen for sex steroids action on bone
Vincenzo Rochira et al.
BONE (2007)
Residual lifetime risk of fractures in women and men
Nguyen D. Nguyen et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2007)
Mutual trans activational repression of Runx2 and the androgen receptor by an impairment of their normal compartmentalization
Hisaya Kawate et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2007)
Targeted ablation of Osteocytes induces osteoporosis with defective mechanotransduction
Sawako Tatsumi et al.
CELL METABOLISM (2007)
The 2.0 Å crystal structure of the ERα ligand-binding domain complexed with lasofoxifene
Felix F. Vajdos et al.
PROTEIN SCIENCE (2007)
Ovariectomy-induced bone loss occurs independently of B cells
Yan Li et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Comparative effects of raloxifene and alendronate on fracture outcomes in postmenopausal women with low bone mass
Robert R. Recker et al.
BONE (2007)
Effects of aromatase inhibitors on human osteoblast and osteoblast-like cells: A possible androgenic bone protective effects induced by exemestane
Yasuhiro Miki et al.
BONE (2007)
Height and bone mineral density in androgen insensitivity syndrome with mutations in the androgen receptor gene
D. L. S. Danilovic et al.
OSTEOPOROSIS INTERNATIONAL (2007)
Osteoblast deletion of exon 3 of the androgen receptor gene results in trabecular bone loss in adult male mice
Amanda J. Notini et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2007)
Selective Androgen Receptor Modulator (SARM) treatment prevents bone loss and reduces body fat in ovariectomized rats
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