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Systems Genetics of Metabolism: The Use of the BXD Murine Reference Panel for Multiscalar Integration of Traits
Penelope A. Andreux et al.
CELL (2012)
Adenosine Signaling Promotes Regeneration of Pancreatic β Cells In Vivo
Olov Andersson et al.
CELL METABOLISM (2012)
Metabolic Disease Drug Discovery - Hitting the Target Is Easier Said Than Done
David E. Moller
CELL METABOLISM (2012)
Studying non-alcoholic fatty liver disease with zebrafish: a confluence of optics, genetics, and physiology
Amnon Schlegel
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Different levels of Notch signaling regulate quiescence, renewal and differentiation in pancreatic endocrine progenitors
Nikolay Ninov et al.
DEVELOPMENT (2012)
Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration
Isabelle Manfroid et al.
DEVELOPMENTAL BIOLOGY (2012)
Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network
Madeline Schaub et al.
DEVELOPMENTAL BIOLOGY (2012)
Transgenic zebrafish illuminate the dynamics of thyroid morphogenesis and its relationship to cardiovascular development
Robert Opitz et al.
DEVELOPMENTAL BIOLOGY (2012)
Voltage-gated calcium channel CACNB2 (β2.1) protein is required in the heart for control of cell proliferation and heart tube integrity
Yelena Chernyavskaya et al.
DEVELOPMENTAL DYNAMICS (2012)
Nutrient Excess Stimulates β-Cell Neogenesis in Zebrafish
Lisette A. Maddison et al.
DIABETES (2012)
Heritable Transmission of Diabetic Metabolic Memory in Zebrafish Correlates With DNA Hypomethylation and Aberrant Gene Expression
Ansgar S. Olsen et al.
DIABETES (2012)
α-Actinin2 is required for the lateral alignment of Z discs and ventricular chamber enlargement during zebrafish cardiogenesis
Jingchun Yang et al.
FASEB JOURNAL (2012)
Emerging applications for zebrafish as a model organism to study oxidative mechanisms and their roles in inflammation and vascular accumulation of oxidized lipids
Longhou Fang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
A monocarboxylate transporter required for hepatocyte secretion of ketone bodies during fasting
Sarah E. Hugo et al.
GENES & DEVELOPMENT (2012)
Efficient Mapping and Cloning of Mutations in Zebrafish by Low-Coverage Whole-Genome Sequencing
Margot E. Bowen et al.
GENETICS (2012)
Mutation mapping and identification by whole-genome sequencing
Ignaty Leshchiner et al.
GENOME RESEARCH (2012)
The basic helix-loop-helix transcription factor, heart and neural crest derivatives expressed transcript 2, marks hepatic stellate cells in zebrafish: Analysis of stellate cell entry into the developing liver
Chunyue Yin et al.
HEPATOLOGY (2012)
Loss of plakophilin 2 disrupts heart development in zebrafish
Miriam A. Moriarty et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY (2012)
Validation of visualized transgenic zebrafish as a high throughput model to assay bradycardia related cardio toxicity risk candidates
Dingsheng Wen et al.
JOURNAL OF APPLIED TOXICOLOGY (2012)
Essential roles of zebrafish bmp2a, fgf10, and fgf24 in the specification of the ventral pancreas
Francois Naye et al.
MOLECULAR BIOLOGY OF THE CELL (2012)
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
Christopher J. L. Murray et al.
LANCET (2012)
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
Theo Vos et al.
LANCET (2012)
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
Rafael Lozano et al.
LANCET (2012)
In vivo genome editing using a high-efficiency TALEN system
Victoria M. Bedell et al.
NATURE (2012)
Clonally dominant cardiomyocytes direct heart morphogenesis
Vikas Gupta et al.
NATURE (2012)
Raise standards for preclinical cancer research
C. Glenn Begley et al.
NATURE (2012)
RNA-guided genetic silencing systems in bacteria and archaea
Blake Wiedenheft et al.
NATURE (2012)
FLASH assembly of TALENs for high-throughput genome editing
Deepak Reyon et al.
NATURE BIOTECHNOLOGY (2012)
Chemical informatics and target identification in a zebrafish phenotypic screen
Christian Laggner et al.
NATURE CHEMICAL BIOLOGY (2012)
The many faces of insulin-like peptide signalling in the brain
Ana M. Fernandez et al.
NATURE REVIEWS NEUROSCIENCE (2012)
TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction
Erin L. Doyle et al.
NUCLEIC ACIDS RESEARCH (2012)
Overexpression of Akt1 Enhances Adipogenesis and Leads to Lipoma Formation in Zebrafish
Che-Yu Chu et al.
PLOS ONE (2012)
Behavioral barcoding in the cloud: embracing data-intensive digital phenotyping in neuropharmacology
David Kokel et al.
TRENDS IN BIOTECHNOLOGY (2012)
Simple Methods for Generating and Detecting Locus-Specific Mutations Induced with TALENs in the Zebrafish Genome
Timothy J. Dahlem et al.
PLOS GENETICS (2012)
Ezetimibe and Simvastatin Reduce Cholesterol Levels in Zebrafish Larvae Fed a High-Cholesterol Diet
Ji Sun Baek et al.
CHOLESTEROL (2012)
Functions of the Wnt/β-catenin pathway in an anemia-induced zebrafish model of cardiomyopathy are location dependent
Tiffany Hoage et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Bisphenol A induces otolith malformations during vertebrate embryogenesis
Yann Gibert et al.
BMC DEVELOPMENTAL BIOLOGY (2011)
Novel Chemical Suppressors of Long QT Syndrome Identified by an In Vivo Functional Screen
David S. Peal et al.
CIRCULATION (2011)
Haploinsufficiency of Target of Rapamycin Attenuates Cardiomyopathies in Adult Zebrafish
Yonghe Ding et al.
CIRCULATION RESEARCH (2011)
The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion
Jinhu Wang et al.
DEVELOPMENT (2011)
Rapid BAC selection for tol2-mediated transgenesis in zebrafish
Jeroen Bussmann et al.
DEVELOPMENT (2011)
Mef2cb regulates late myocardial cell addition from a second heart field-like population of progenitors in zebrafish
Savo Lazic et al.
DEVELOPMENTAL BIOLOGY (2011)
Retinoic Acid Production by Endocardium and Epicardium Is an Injury Response Essential for Zebrafish Heart Regeneration
Kazu Kikuchi et al.
DEVELOPMENTAL CELL (2011)
Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin
Seok-Hyung Kim et al.
DISEASE MODELS & MECHANISMS (2011)
Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in zebrafish
Jason R. Becker et al.
DISEASE MODELS & MECHANISMS (2011)
Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish
Agata Jurczyk et al.
GENERAL AND COMPARATIVE ENDOCRINOLOGY (2011)
A versatile gene trap to visualize and interrogate the function of the vertebrate proteome
Le A. Trinh et al.
GENES & DEVELOPMENT (2011)
In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish
Longhou Fang et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Adipose tissue remodeling and obesity
Kai Sun et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
DHODH modulates transcriptional elongation in the neural crest and melanoma
Richard Mark White et al.
NATURE (2011)
A TALE nuclease architecture for efficient genome editing
Jeffrey C. Miller et al.
NATURE BIOTECHNOLOGY (2011)
Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)
Jeffry D. Sander et al.
NATURE METHODS (2011)
In vivo protein trapping produces a functional expression codex of the vertebrate proteome
Karl J. Clark et al.
NATURE METHODS (2011)
How were new medicines discovered?
David C. Swinney et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Molecular control of endothelial cell behaviour during blood vessel morphogenesis
Shane P. Herbert et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
Tomas Cermak et al.
NUCLEIC ACIDS RESEARCH (2011)
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
Claudio Mussolino et al.
NUCLEIC ACIDS RESEARCH (2011)
A High-Throughput Screen for Tuberculosis Progression
Ralph Carvalho et al.
PLOS ONE (2011)
The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish
Yme U. van der Velden et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation
Meritxell Rovira et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Human Fatty Liver Disease: Old Questions and New Insights
Jonathan C. Cohen et al.
SCIENCE (2011)
Transient Regenerative Potential of the Neonatal Mouse Heart
Enzo R. Porrello et al.
SCIENCE (2011)
Enhancing the Efficiency of N-Ethyl-N-Nitrosourea-Induced Mutagenesis in the Zebrafish
Nicolas Rohner et al.
ZEBRAFISH (2011)
Multifactorial Origins of Heart and Gut Defects in nipbl-Deficient Zebrafish, a Model of Cornelia de Lange Syndrome
Akihiko Muto et al.
PLOS BIOLOGY (2011)
Large Scale Zebrafish-Based In vivo Small Molecule Screen
Jijun Hao et al.
Jove-Journal of Visualized Experiments (2011)
Electrocardiogram Signals to Assess Zebrafih Heart Regeneration: Implication of Long QT Intervals
Fei Yu et al.
ANNALS OF BIOMEDICAL ENGINEERING (2010)
Long-term warm or cold acclimation elicits a specific transcriptional response and affects energy metabolism in zebrafish
Lucia Vergauwen et al.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2010)
A dual role for ErbB2 signaling in cardiac trabeculation
Jiandong Liu et al.
DEVELOPMENT (2010)
Distinct Troponin C Isoform Requirements in Cardiac and Skeletal Muscle
Vanessa M. Sogah et al.
DEVELOPMENTAL DYNAMICS (2010)
White Adipose Tissue Development in Zebrafish Is Regulated by Both Developmental Time and Fish Size
Dru Imrie et al.
DEVELOPMENTAL DYNAMICS (2010)
Predominant cone photoreceptor dysfunction in a hyperglycaemic model of non-proliferative diabetic retinopathy
Yolanda Alvarez et al.
DISEASE MODELS & MECHANISMS (2010)
Oxidized Cholesteryl Esters and Phospholipids in Zebrafish Larvae Fed a High Cholesterol Diet MACROPHAGE BINDING AND ACTIVATION
Longhou Fang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Ang2/Fat-Free Is a Conserved Subunit of the Golgi-associated Retrograde Protein Complex
F. Javier Perez-Victoria et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
Primary contribution to zebrafish heart regeneration by gata4+ cardiomyocytes
Kazu Kikuchi et al.
NATURE (2010)
Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
Chris Jopling et al.
NATURE (2010)
Rapid behavior-based identification of neuroactive small molecules in the zebrafish
David Kokel et al.
NATURE CHEMICAL BIOLOGY (2010)
High-throughput in vivo vertebrate screening
Carlos Pardo-Martin et al.
NATURE METHODS (2010)
The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome
Jung Sub Lim et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2010)
Advances in understanding tissue regenerative capacity and mechanisms in animals
Kenneth D. Poss
NATURE REVIEWS GENETICS (2010)
Identification of Novel Inhibitors of Dietary Lipid Absorption Using Zebrafish
Justin D. Clifton et al.
PLOS ONE (2010)
Suppression of Alk8-mediated Bmp signaling cell-autonomously induces pancreatic β-cells in zebrafish
Won-Suk Chung et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury
Trista E. North et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Cardiac conduction is required to preserve cardiac chamber morphology
Neil C. Chi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Optogenetic Control of Cardiac Function
Aristides B. Arrenberg et al.
SCIENCE (2010)
Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome
Daniel G. Gibson et al.
SCIENCE (2010)
Identification of a Primary Target of Thalidomide Teratogenicity
Takumi Ito et al.
SCIENCE (2010)
Blood Sugar Measurement in Zebrafish Reveals Dynamics of Glucose Homeostasis
Stefani C. Eames et al.
ZEBRAFISH (2010)
Can Animal Models of Disease Reliably Inform Human Studies?
H. Bart van der Worp et al.
PLOS MEDICINE (2010)
Micro-Electrocardiograms to Study Post-Ventricular Amputation of Zebrafish Heart
Ping Sun et al.
ANNALS OF BIOMEDICAL ENGINEERING (2009)
Genome-wide analysis of Tol2 transposon reintegration in zebrafish
Igor Kondrychyn et al.
BMC GENOMICS (2009)
Drug-Sensitized Zebrafish Screen Identifies Multiple Genes, Including GINS3, as Regulators of Myocardial Repolarization
David J. Milan et al.
CIRCULATION (2009)
Vascular Lipid Accumulation, Lipoprotein Oxidation, and Macrophage Lipid Uptake in Hypercholesterolemic Zebrafish
Konstantin Stoletov et al.
CIRCULATION RESEARCH (2009)
Sarcomere Mutations in Cardiomyopathy With Left Ventricular Hypertrabeculation
Lisa M. Dellefave et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2009)
TNFα-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish s-adenosylhomocysteine hydrolase
Randolph P. Matthews et al.
DEVELOPMENT (2009)
Selective plane illumination microscopy techniques in developmental biology
Jan Huisken et al.
DEVELOPMENT (2009)
Plakoglobin has both structural and signalling roles in zebrafish development
Eva D. Martin et al.
DEVELOPMENTAL BIOLOGY (2009)
Regeneration of the Pancreas in Adult Zebrafish
Jennifer B. Moss et al.
DIABETES (2009)
Differential tissue-specific distribution of transcripts for the duplicated fatty acid-binding protein 10 (fabp10) genes in embryos, larvae and adult zebrafish (Danio rerio)
Ananda B. Venkatachalam et al.
FEBS JOURNAL (2009)
Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio)
Edward J. Flynn et al.
JOURNAL OF LIPID RESEARCH (2009)
Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy
David Hassel et al.
NATURE MEDICINE (2009)
Targeted mutagenesis in zebrafish using customized zinc-finger nucleases
Jonathan E. Foley et al.
NATURE PROTOCOLS (2009)
Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas
Michael J. Parsons et al.
MECHANISMS OF DEVELOPMENT (2009)
Cardiac Hypertrophy Involves Both Myocyte Hypertrophy and Hyperplasia in Anemic Zebrafish
Xiaojing Sun et al.
PLOS ONE (2009)
Distinct populations of quiescent and proliferative pancreatic β-cells identified by HOTcre mediated labeling
Daniel Hesselson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors
Jens Boch et al.
SCIENCE (2009)
Arterial-Venous Segregation by Selective Cell Sprouting: An Alternative Mode of Blood Vessel Formation
Shane P. Herbert et al.
SCIENCE (2009)
Growth and Survival of Zebrafish (Danio rerio) Fed Different Commercial and Laboratory Diets
Anthony J. Siccardi et al.
ZEBRAFISH (2009)
Semi-automated Optical Heartbeat Analysis of Small Hearts
Karen Ocorr et al.
Jove-Journal of Visualized Experiments (2009)
Functional and developmental analysis of the blood-brain barrier in zebrafish
Jae-Yeon Jeong et al.
BRAIN RESEARCH BULLETIN (2008)
Deficient zebrafish ether-a-go-go-related gene channel gating causes Short-QT syndrome in zebrafish reggae mutants
David Hassel et al.
CIRCULATION (2008)
Endothelial Signals Modulate Hepatocyte Apicobasal Polarization in Zebrafish
Takuya F. Sakaguchi et al.
CURRENT BIOLOGY (2008)
Intra-endodermal interactions are required for pancreatic β cell induction
Won-Suk Chung et al.
DEVELOPMENTAL CELL (2008)
Bmp2 Signaling Regulates the Hepatic versus Pancreatic Fate Decision
Won-Suk Chung et al.
DEVELOPMENTAL CELL (2008)
Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas
P. Duc Si Dong et al.
GENES & DEVELOPMENT (2008)
Rapid Open-Source engineering of customized zinc-finger nucleases for highly efficient gene modification
Morgan L. Maeder et al.
MOLECULAR CELL (2008)
Reprogramming pancreatic exocrine cells to β-cells
[Anonymous]
CLINICAL PHARMACOLOGY & THERAPEUTICS (2008)
Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases
Yannick Doyon et al.
NATURE BIOTECHNOLOGY (2008)
Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases
Xiangdong Meng et al.
NATURE BIOTECHNOLOGY (2008)
Methods for generating and colonizing gnotobiotic zebrafish
Linh N. Pham et al.
NATURE PROTOCOLS (2008)
How to create the vascular tree? (Latest) help from the zebrafish
Danila Baldessari et al.
PHARMACOLOGY & THERAPEUTICS (2008)
Genetic dissection of neural circuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish
Kazuhide Asakawa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
In vivo cardiac imaging of adult zebrafish using high frequency ultrasound (45-75 mhz)
Lei Sun et al.
ULTRASOUND IN MEDICINE AND BIOLOGY (2008)
Genetic and physiologic dissection of the vertebrate cardiac conduction system
Neil C. Chi et al.
PLOS BIOLOGY (2008)
In vivo reprogramming of adult pancreatic exocrine cells to β-cells
Qiao Zhou et al.
NATURE (2008)
Insertional mutagenesis by the Tol2 transposon-mediated enhancer trap approach generated mutations in two developmental genes: tcf7 and synembryn-like
Saori Nagayoshi et al.
DEVELOPMENT (2008)
Gata5 and Gata6 are functionally redundant in zebrafish for specification of cardiomyocytes
Audrey Holtzinger et al.
DEVELOPMENTAL BIOLOGY (2007)
Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota
Jennifer M. Bates et al.
CELL HOST & MICROBE (2007)
Reciprocal endoderm-mesoderm interactions mediated by fgf24 and fgf10 govern pancreas development
Isabelle Manfroid et al.
DEVELOPMENT (2007)
Lessons from ''lower'' organisms: What worms, flies, and zebrafish can teach us about human energy metabolism
Amnon Schlegel et al.
PLOS GENETICS (2007)
The Tol2kit:: A multisite Gateway-based construction kit for Tol2 transposon transgenesis constructs
Kristen M. Kwan et al.
DEVELOPMENTAL DYNAMICS (2007)
SIRT1 controls endothelial angiogenic functions during vascular growth
Michael Potente et al.
GENES & DEVELOPMENT (2007)
Ligand activation of LXRβ reverses atherosclerosis and cellular cholesterol overload in mice lacking LXRα and apoE
Michelle N. Bradley et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Germline gain-of-function mutations in RAF1 cause Noonan syndrome
M. Abdur Razzaque et al.
NATURE GENETICS (2007)
Laminin-α4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells
Ralph Knoell et al.
CIRCULATION (2007)
Zebrafish model for human long QT syndrome
Rima Arnaout et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Creation of a genetic model of obesity in a teleost
Youngsup Song et al.
FASEB JOURNAL (2007)
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis
Trista E. North et al.
NATURE (2007)
Animal models of human disease: zebrafish swim into view
Graham J. Lieschke et al.
NATURE REVIEWS GENETICS (2007)
Conditional targeted cell ablation in zebrafish: A new tool for regeneration studies
Silvia Curado et al.
DEVELOPMENTAL DYNAMICS (2007)
Targeting neural circuitry in zebrafish using GAL4 enhancer trapping
Ethan K. Scott et al.
NATURE METHODS (2007)
Fgf10 regulates hepatopancreatic ductal system patterning and differentiation
P. Duc Si Dong et al.
NATURE GENETICS (2007)
Larval zebrafish as a model for glucose metabolism: expression of phosphoenolpyruvate carboxykinase as a marker for exposure to anti-diabetic compounds
B. Elo et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2007)
Targeted ablation of beta cells in the embryonic zebrafish pancreas using E-coli nitroreductase
Harshan Pisharath et al.
MECHANISMS OF DEVELOPMENT (2007)
A new time-scale for ray-finned fish evolution
Imogen A. Hurley et al.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2007)
Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries
Arndt F. Siekmann et al.
NATURE (2007)
Illuminating cardiac development: Advances in imaging add new dimensions to the utility of zebrafish genetics
Jeffrey J. Schoenebeck et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2007)
Microsomal triglyceride transfer protein is required for yolk lipid utilization and absorption of dietary lipids in zebrafish larvae
Amnon Schlegel et al.
BIOCHEMISTRY (2006)
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
Kevin A. D'Amour et al.
NATURE BIOTECHNOLOGY (2006)
Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection
John F. Rawls et al.
CELL (2006)
The bHLH transcription factor hand2 is essential for noradrenergic differentiation of sympathetic neurons
Marsha E. Lucas et al.
DEVELOPMENT (2006)
Functional dissection of the Tol2 transposable element identified the minimal cis-sequence and a highly repetitive sequence in the subterminal region essential for transposition
Akihiro Urasaki et al.
GENETICS (2006)
A clinical drug library screen identifies astemizole as an antimalarial agent
Curtis R. Chong et al.
NATURE CHEMICAL BIOLOGY (2006)
Gene-breaking transposon mutagenesis reveals an essential role for histone H2afza in zebrafish larval development
Sridhar Sivasubbu et al.
MECHANISMS OF DEVELOPMENT (2006)
In vivo recording of adult zebrafish electrocardiogram and assessment of drug-induced QT prolongation
David J. Milan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)
Zebrafish fat-free is required for intestinal lipid absorption and Golgi apparatus structure
SY Ho et al.
CELL METABOLISM (2006)
Notch1b and neuregulin are required for specification of central cardiac conduction tissue
DJ Milan et al.
DEVELOPMENT (2006)
Calcium extrusion is critical for cardiac morphogenesis and rhythm in embryonic zebrafish hearts
AM Ebert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Mutation in sodium-calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish
AD Langenbacher et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development
D Beis et al.
DEVELOPMENT (2005)
A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease
KC Sadler et al.
DEVELOPMENT (2005)
VEGF-PLCγ1 pathway controls cardiac contractility in the embryonic heart
W Rottbauer et al.
GENES & DEVELOPMENT (2005)
Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss
J Schönberger et al.
NATURE GENETICS (2005)
In vivo drug discovery in the zebrafish
LI Zon et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
Gnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota
JF Rawls et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
A zebrafish model for pyruvate dehydrogenase deficiency: Rescue of neurological dysfunction and embryonic lethality using a ketogenic diet
MR Taylor et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
TILLING - a high-throughput harvest for functional genomics
DL Stemple
NATURE REVIEWS GENETICS (2004)
Sudden death associated with short-QT syndrome linked to mutations in HERG
R Brugada et al.
CIRCULATION (2004)
Phylogenetic timing of the fish-specific genome duplication correlates with the diversification of teleost fish
S Hoegg et al.
JOURNAL OF MOLECULAR EVOLUTION (2004)
Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation
RT Peterson et al.
NATURE BIOTECHNOLOGY (2004)
Zebrafish embryos express an orthologue of HERG and are sensitive toward a range and are of QT-prolonging drugs inducing severe arrhythmia
U Langheinrich et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2003)
The Wnt/β-catenin pathway regulates cardiac valve formation
AFL Hurlstone et al.
NATURE (2003)
Regulation and mechanisms of mammalian double-strand break repair
K Valerie et al.
ONCOGENE (2003)
Formation of the digestive system in zebrafish. II. Pancreas morphogenesis
HA Field et al.
DEVELOPMENTAL BIOLOGY (2003)
Drugs that induce repolarization abnormalities cause bradycardia in zebrafish
DJ Milan et al.
CIRCULATION (2003)
Efficient target-selected mutagenesis in zebrafish
E Wienholds et al.
GENOME RESEARCH (2003)
From endoderm formation to liver and pancreas development in zebrafish
EA Ober et al.
MECHANISMS OF DEVELOPMENT (2003)
I-SceI meganuclease mediates highly efficient transgenesis in fish
V Thermes et al.
MECHANISMS OF DEVELOPMENT (2002)
Arteries and veins: Making a difference with zebrafish
ND Lawson et al.
NATURE REVIEWS GENETICS (2002)
Retinoic acid signaling is required for a critical early step in zebrafish pancreatic development
D Stafford et al.
CURRENT BIOLOGY (2002)
Cardiac troponin T is essential in sarcomere assembly and cardiac contractility
AJ Sehnert et al.
NATURE GENETICS (2002)
Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin
XL Xu et al.
NATURE GENETICS (2002)
Vhnf1, the MODY5 and familial GCKD-associated gene, regulates regional specification of the zebrafish gut, pronephros, and hindbrain
ZX Sun et al.
GENES & DEVELOPMENT (2001)
The art and design of genetic screens: Zebrafish
EE Patton et al.
NATURE REVIEWS GENETICS (2001)
The slow mo mutation reduces pacemaker current and heart rate in adult zebrafish
KS Warren et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2001)
UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish
EC Walsh et al.
SCIENCE (2001)
Genetic analysis of digestive physiology using fluorescent phospholipid reporters
SA Farber et al.
SCIENCE (2001)
Endocrine pancreas plasticity under physiological and pathological conditions
C Bernard-Kargar et al.
DIABETES (2001)
Identification of a functional transposase of the Tol2 element, an Ac-like element from the Japanese medaka fish, and its transposition in the zebrafish germ lineage
K Kawakami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Effective targeted gene 'knockdown' in zebrafish
A Nasevicius et al.
NATURE GENETICS (2000)
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