4.8 Article

Coarse-Graining the Fluid Flow around a Human Sperm

Journal

PHYSICAL REVIEW LETTERS
Volume 118, Issue 12, Pages -

Publisher

AMER PHYSICAL SOC
DOI: 10.1103/PhysRevLett.118.124501

Keywords

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Funding

  1. Kyoto University Hakubi Project
  2. Supporting Program for Interaction-based Initiative Team Studies (SPIRITS)
  3. MRC Special Training Fellowship [G0600178]
  4. National Institutes of Health Research (NIHR) [HCS SCL-2014-05-001] Funding Source: National Institutes of Health Research (NIHR)
  5. Medical Research Council [G0600178] Funding Source: researchfish
  6. National Institute for Health Research [HCS SCL-2014-05-001] Funding Source: researchfish
  7. MRC [G0600178] Funding Source: UKRI

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The flagellar beat is extracted from human sperm digital imaging microscopy and used to determine the flow around the cell and its trajectory, via boundary element simulation. Comparison of the predicted cell trajectory with observation demonstrates that simulation can predict fine-scale sperm dynamics at the qualitative level. The flow field is also observed to reduce to a time-dependent summation of regularized Stokes flow singularities, approximated at leading order by a blinking force triplet. Such regularized singularity decompositions may be used to upscale cell level detail into population models of human sperm motility.

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