Journal
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
Volume 48, Issue 9, Pages 3037-3050Publisher
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10803-018-3555-4
Keywords
Williams syndrome; Intellectual disability; Autism spectrum disorders; Social communication
Categories
Funding
- NIMH [R03 MH069400]
- University of Wisconsin-Milwaukee Graduate School Research Committee Award
- Williams Syndrome Association (WSA) [0110]
- National Institute of Neurological Disorders and Stroke [R01 NS35102]
- National Institute of Child Health and Human Development [R37 HD29957]
- Williams Syndrome Association [WSA 0104, WSA 0111]
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To characterize autism spectrum-related symptomatology in children with Williams syndrome (WS) with phrase speech or fluent language, the Autism Diagnostic Observation Schedule Module 2 or 3 was administered. The cutoff for autism spectrum was met by 35% (14/40) who completed Module 2 and 30% (18/60) who completed Module 3. Similarities and differences in socio-communicative strengths and weaknesses as a function of language ability were identified. Symptom severity was negatively associated with IQ for participants with phrase speech but not for those with fluent language. The findings suggest an elevated risk of ASD for individuals with WS relative to the general population and contribute to a more nuanced sense of the socio-communicative functioning of children with WS.
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