Journal
PHARMACOTHERAPY
Volume 37, Issue 11, Pages 1469-1478Publisher
WILEY
DOI: 10.1002/phar.2013
Keywords
prescription drugs; drug pricing; out-of-pocket costs; drug costs; pharmaceutical policy
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Funding
- John and Laura Arnold Foundation
- T32 NRSA Training Grant from the Agency for Healthcare Research and Quality
- Jayne Koskinas Ted Giovanis Foundation for Health and Policy
- QuintilesIMS
- OptumRx's National PT Committee
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The high prices of specialty pharmaceuticals are causing some public programs to ration care and many private insurers, including Medicare drug plans, to place specialty drugs on high cost-sharing tiers. As a result, access to these drugs is often restricted, and only a small portion of the population with a disease may receive treatment. This concern has generated a wide range of proposed solutions. We conducted a literature review and identified 52 solutions in the peer-reviewed literature that we classified into five broad categories: revising the patent system, encouraging research to increase development of new drugs, altering pharmaceutical regulation, decreasing market demand, and developing innovative pricing strategies. We discuss the rationale for these five approaches and summarize the proposed solutions. We also discuss four empirical issues that are particularly important in any discussion of policy options.
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