Related references
Note: Only part of the references are listed.Endocytosis following dopamine D2 receptor activation is critical for neuronal activity and dendritic spine formation via Rabex-5/PDGFRβ signaling in striatopallidal medium spiny neurons
N. Shioda et al.
MOLECULAR PSYCHIATRY (2017)
Systematic Review and Network Meta-analysis of Idiopathic Pulmonary Fibrosis Treatments
Kelly Fleetwood et al.
Journal of Managed Care & Specialty Pharmacy (2017)
CX3CL1/CX3CR1 Axis Plays a Key Role in Ischemia-Induced Oligodendrocyte Injury via p38MAPK Signaling Pathway
Xiao-Mei Wu et al.
MOLECULAR NEUROBIOLOGY (2016)
Insulator dysfunction and oncogene activation in IDH mutant gliomas
William A. Flavahan et al.
NATURE (2016)
PDGFR-β Plays a Key Role in the Ectopic Migration of Neuroblasts in Cerebral Stroke
Hikari Sato et al.
STEM CELLS (2016)
Syndecan-4 enhances PDGF-BB activity in diabetic wound healing
Subhamoy Das et al.
ACTA BIOMATERIALIA (2016)
Glioma-Derived Platelet-Derived Growth Factor-BB Recruits Oligodendrocyte Progenitor Cells via Platelet-Derived Growth Factor Receptor-α and Remodels Cancer Stroma
Yang Zheng et al.
AMERICAN JOURNAL OF PATHOLOGY (2016)
Mesenchymal stem cells generate pericytes to promote tumor recurrence via vasculogenesis after stereotactic body radiation therapy
Huan-Huan Wang et al.
CANCER LETTERS (2016)
Clarification of mural cell coverage of vascular endothelial cells by live imaging of zebrafish
Koji Ando et al.
DEVELOPMENT (2016)
Olaratumab and doxorubicin versus doxorubicin alone for treatment of soft-tissue sarcoma: an open-label phase 1b and randomised phase 2 trial
William D. Tap et al.
LANCET (2016)
Pericyte-fibroblast transition promotes tumor growth and metastasis
Kayoko Hosaka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
The progress in understanding and treatment of diabetic retinopathy
Alan W. Stitt et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2016)
Signals and Receptors
Carl-Henrik Heldin et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages
Yunlong Yang et al.
NATURE COMMUNICATIONS (2016)
High glucose induces platelet-derived growth factor-C via carbohydrate response element-binding protein in glomerular mesangial cells
Hiroya Kitsunai et al.
PHYSIOLOGICAL REPORTS (2016)
A Point Mutation in PDGFRB Causes Autosomal-Dominant Penttinen Syndrome
Jennifer J. Johnston et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2015)
Safety and tolerability of intracerebroventricular PDGF-BB in Parkinson's disease patients
Gesine Paul et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Novel Overgrowth Syndrome Phenotype Due to Recurrent De Novo PDGFRB Mutation
Toshiki Takenouchi et al.
JOURNAL OF PEDIATRICS (2015)
PDGFRα plays a crucial role in connective tissue remodeling
Shinjiro Horikawa et al.
SCIENTIFIC REPORTS (2015)
Relationships among Parvalbumin-Immunoreactive Neuron Density, Phase-Locked Gamma Oscillations, and Autistic/Schizophrenic Symptoms in PDGFR-β Knock-Out and Control Mice
Tomoya Nakamura et al.
PLOS ONE (2015)
Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification
Michael Vanlandewijck et al.
PLOS ONE (2015)
Inflammation-induced endothelial cell-derived extracellular vesicles modulate the cellular status of pericytes
Seiji Yamamoto et al.
SCIENTIFIC REPORTS (2015)
Neuroprotective strategies against calpain-mediated neurodegeneration
Aysegul Yildiz-Unal et al.
NEUROPSYCHIATRIC DISEASE AND TREATMENT (2015)
Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling
Susann Weissmueller et al.
CELL (2014)
Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease
Curtis R. French et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
The Roles of PDGF in Development and During Neurogenesis in the Normal and Diseased Nervous System
Keiko Funa et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2014)
PDGF and the progression of renal disease
Peter Boor et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2014)
Platelet-derived growth factor in glioblastoma-driver or biomarker?
Bengt Westermark
UPSALA JOURNAL OF MEDICAL SCIENCES (2014)
Mutations in PDGFRB Cause Autosomal-Dominant Infantile Myofibromatosis
John A. Martignetti et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice
Annika Keller et al.
NATURE GENETICS (2013)
Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis
Shin H. Kang et al.
NATURE NEUROSCIENCE (2013)
FUNCTIONAL ANALYSIS OF PLATELET-DERIVED GROWTH FACTOR RECEPTOR-β IN NEURAL STEM/PROGENITOR CELLS
G. Xu et al.
NEUROSCIENCE (2013)
PDGF Suppresses Oxidative Stress Induced Ca2+ Overload and Calpain Activation in Neurons
Lian-Shun Zheng et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
Human Bone Marrow-Derived Mesenchymal Stem Cells Suppress Human Glioma Growth Through Inhibition of Angiogenesis
Ivy A. W. Ho et al.
STEM CELLS (2013)
Multifarious functions of PDGFs and PDGFRs in tumor growth and metastasis
Yihai Cao
TRENDS IN MOLECULAR MEDICINE (2013)
Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodelling and metastasis
Kayoko Hosaka et al.
NATURE COMMUNICATIONS (2013)
Changes in Otx2 and Parvalbumin Immunoreactivity in the Superior Colliculus in the Platelet-Derived Growth Factor Receptor-β Knockout Mice
Juanjuan Zhao et al.
BIOMED RESEARCH INTERNATIONAL (2013)
Involvement of PDGF in Fibrosis and Scleroderma: Recent Insights from Animal Models and Potential Therapeutic Opportunities
Tomoaki Iwayama et al.
CURRENT RHEUMATOLOGY REPORTS (2013)
Platelet-Derived Growth Factor C Deficiency in C57BL/6 Mice Leads to Abnormal Cerebral Vascularization, Loss of Neuroependymal Integrity, and Ventricular Abnormalities
Linda Fredriksson et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity
Youngmi Kim et al.
GENES & DEVELOPMENT (2012)
Aberrant hippocampal spine morphology and impaired memory formation in neuronal platelet-derived growth factor beta-receptor lacking mice
Norifumi Shioda et al.
HIPPOCAMPUS (2012)
PDGFR-β as a positive regulator of tissue repair in a mouse model of focal cerebral ischemia
Jie Shen et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)
Platelet-Derived Growth Factor-BB Restores Human Immunodeficiency Virus Tat-Cocaine-Mediated Impairment of Neurogenesis: Role of TRPC1 Channels
Honghong Yao et al.
JOURNAL OF NEUROSCIENCE (2012)
Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial
Winette T. A. van der Graaf et al.
LANCET (2012)
Oligodendroglia metabolically support axons and contribute to neurodegeneration
Youngjin Lee et al.
NATURE (2012)
PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells
Yuan Xue et al.
NATURE MEDICINE (2012)
History of Discovery Platelet-Derived Growth Factor
Daniel F. Bowen-Pope et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2011)
Deletion of platelet-derived growth factor receptor-β improves diabetic nephropathy in Ca2+/calmodulin-dependent protein kinase IIα (Thr286Asp) transgenic mice
H. Suzuki et al.
DIABETOLOGIA (2011)
Platelet-Derived Growth Factor-Responsive Neural Precursors Give Rise to Myelinating Oligodendrocytes After Transplantation into the Spinal Cords of Contused Rats and Dysmyelinated Mice
Jason R. Plemel et al.
GLIA (2011)
Roles of PDGF receptor-beta in the structure and function of postnatal kidney glomerulus
Taizo Nakagawa et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2011)
Platelet-derived growth factor mediates survival of leukemic large granular lymphocytes via an autocrine regulatory pathway
Jun Yang et al.
BLOOD (2010)
Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch
Wei Ding et al.
BLOOD (2010)
Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
Roel G. W. Verhaak et al.
CANCER CELL (2010)
A Novel Signaling Axis of Matriptase/PDGF-D/β-PDGFR in Human Prostate Cancer
Carolyn V. Ustach et al.
CANCER RESEARCH (2010)
Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3β phosphorylation
Zhongshu Tang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Pericytes regulate the blood-brain barrier
Annika Armulik et al.
NATURE (2010)
Pericytes are required for blood-brain barrier integrity during embryogenesis
Richard Daneman et al.
NATURE (2010)
Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia
Franck Lebrin et al.
NATURE MEDICINE (2010)
Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging
Robert D. Bell et al.
NEURON (2010)
PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets
Xu Hou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex
Ann Hye-Ryong Shim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Serum levels of platelet-derived growth factor BB homodimers are increased in male children with autism
Masanobu Kajizuka et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2010)
PDGF-C Mediates the Angiogenic and Tumorigenic Properties of Fibroblasts Associated with Tumors Refractory to Anti-VEGF Treatment
Yongping Crawford et al.
CANCER CELL (2009)
Ligand-Dependent Platelet-Derived Growth Factor Receptor (PDGFR)-α Activation Sensitizes Rare Lung Cancer and Sarcoma Cells to PDGFR Kinase Inhibitors
Ultan McDermott et al.
CANCER RESEARCH (2009)
Increased PDGFRα Activation Disrupts Connective Tissue Development and Drives Systemic Fibrosis
Lorin E. Olson et al.
DEVELOPMENTAL CELL (2009)
Activation of MAP kinases, Akt and PDGF receptors in injured peripheral nerves
Takashi Yamazaki et al.
JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM (2009)
Activation of PKC-δ and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy
Pedro Geraldes et al.
NATURE MEDICINE (2009)
PDGF-C Induces Maturation of Blood Vessels in a Model of Glioblastoma and Attenuates the Response to Anti-VEGF Treatment
Emmanuelle di Tomaso et al.
PLOS ONE (2009)
Glioblastoma Subclasses Can Be Defined by Activity among Signal Transduction Pathways and Associated Genomic Alterations
Cameron Brennan et al.
PLOS ONE (2009)
Distinctions between fetal and adult human platelet-derived growth factor-responsive neural precursors
Andrew Chojnacki et al.
ANNALS OF NEUROLOGY (2008)
Notch signaling regulates platelet-derived growth factor receptor-β expression in vascular smooth muscle cells
Shaobo Jin et al.
CIRCULATION RESEARCH (2008)
Role of platelet-derived growth factors in physiology and medicine
Johanna Andrae et al.
GENES & DEVELOPMENT (2008)
PDGF receptor beta is a potent regulator of mesenchymal stromal cell function
Ayano Tokunaga et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2008)
Characterization of neuroprogenitor cells expressing the PDGF β-receptor within the subventricular zone of postnatal mice
Yoko Ishii et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2008)
Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke
Enming J. Su et al.
NATURE MEDICINE (2008)
Remyelination in the CNS: from biology to therapy
Robin J. M. Franklin et al.
NATURE REVIEWS NEUROSCIENCE (2008)
Neurovascular signalling defects in neurodegeneration
Serena Zacchigna et al.
NATURE REVIEWS NEUROSCIENCE (2008)
Genetic association between 5′-upstream single-nucleotide polymorphisms of PDGFRB and schizophrenia in a Korean population
Hak-Jae Kim et al.
SCHIZOPHRENIA RESEARCH (2008)
Platelet-derived growth factor-D overexpression contributes to epithelial-mesenchymal transition of PC3 prostate cancer cells
Dejuan Kong et al.
STEM CELLS (2008)
Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content
Marya F. McCarty et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Platelet-derived growth factor (PDGF)-BB inhibits AMPA receptor-mediated synaptic transmission via PDGF receptor-β in murine nucleus tractus solitarius
Yoshiaki Ohi et al.
BRAIN RESEARCH (2007)
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
Tracy T. Batchelor et al.
CANCER CELL (2007)
Mesenchymal stem cells and neovascularization: role of platelet-derived growth factor receptors
Stephen G. Ball et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2007)
Platelet-derived growth factor-β receptor activation is essential for fibroblast and pericyte recruitment during cutaneous wound healing
Vineeth S. Rajkumar et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Mouse brains deficient in neuronal PDGF receptor-β develop normally but are vulnerable to injury
Yoko Ishii et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Autocrine PDGFR signaling promotes mammary cancer metastasis
Martin Jechlinger et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Deletion of the PDGFR-β gene affects key fibroblast functions important for wound healing
ZY Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Correlation of KIT and platelet-derived growth factor receptor α mutations with gene activation and expression profiles in gastrointestinal stromal tumors
HJ Kang et al.
ONCOGENE (2005)
Molecular and clinical analysis of locally advanced dermatofibrosarcoma protuberans treated with imatinib: Imatinib target exploration consortium study B2225
GA McArthur et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate
M Furuhashi et al.
CANCER RESEARCH (2004)
The PDGF B-chain is involved in the ontogenic susceptibility of the developing rat brain to NMDA toxicity
T Egawa-Tsuzuki et al.
EXPERIMENTAL NEUROLOGY (2004)
Insight into the physiological functions of PDGF through genetic studies in mice
C Betsholtz
CYTOKINE & GROWTH FACTOR REVIEWS (2004)
PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRα-induced myeloproliferative disease
J Cools et al.
CANCER CELL (2003)
CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy
A Pardanani et al.
BLOOD (2003)
A D2 class dopamine receptor transactivates a receptor tyrosine kinase to inhibit NMDA receptor transmission
SA Kotecha et al.
NEURON (2002)
Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23
HMD Gurling et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2001)
Human breast carcinoma desmoplasia is PDGF initiated
ZM Shao et al.
ONCOGENE (2000)