4.5 Letter

Occurrence of Crohn's disease with Parkinson's disease

Journal

PARKINSONISM & RELATED DISORDERS
Volume 37, Issue -, Pages 116-117

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.parkreldis.2017.01.013

Keywords

Co-occurrence; Crohn's disease; LRRK2; Parkinson's disease

Funding

  1. NIH/NINDS [P50 NS072187]
  2. Jaye F. and Betty F. Dyer Foundation
  3. Max Kade Foundation
  4. Mayo Clinic Center for Regenerative Medicine
  5. Allergan Medical Educational Grant
  6. Mayo Clinic Center for Individualized Medicine
  7. Mayo Clinic Neuroscience Focused Research Team/Cecilia and Dan Carmichael Family Foundation
  8. James C. and Sarah K. Kennedy Fund for Neurodegenerative Disease Research at Mayo Clinic in Florida
  9. Sol Goldman Charitable Trust

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We retrospectively investigated the co-occurrence of Crohn's disease in a cohort of 876 patients with Parkinson's disease, based on the observation that LRRK2 is a shared genetic risk factor. We identified 2 patients with Crohn's disease; this number was consistent with the number of cases expected in the general population. (C) 2017 Elsevier Ltd. All rights reserved.

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