4.2 Article

A New Formulation Based on Ozonated Sunflower Seed Oil: In Vitro Antibacterial and Safety Evaluation

Journal

OZONE-SCIENCE & ENGINEERING
Volume 39, Issue 3, Pages 139-147

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/01919512.2016.1272405

Keywords

Ozone; Antibacterial Activity; Cytotoxicity; Dermatological Gel; Ozonated Sunflower Seed Oil; Preservative Efficiency

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The objective of this study was to investigate the potential in vitro biological properties of Oz.Or.Oil 30, a new formulation composed of 30% ozonated sunflower seed oil, which is believed to keep skin smooth and moisturized, supporting repair processes, tissue regeneration and re-epithelialization of wounds. The antibacterial activity, the qualitative and quantitative evaluation of the cytotoxic effect of the formulation on cultures of Vero cells and 3T3 fibroblasts showed that Oz.Or.Oil 30 merits further in vivo study using clinical-laboratory correlations, because it could be suggested as an alternative therapy against bacterial and fungal diseases.

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