Journal
ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES
Volume 48, Issue 1, Pages 73-81Publisher
SPRINGER
DOI: 10.1007/s11084-017-9541-6
Keywords
Identity elements; Operational code; Anticodon code; tRNA evolution; Information theory
Categories
Funding
- Consejo Nacional de Ciencia y Tecnologia (CONACYT) [737920]
- UNAM, Mexico [PAPIIT-IN224015]
Ask authors/readers for more resources
The decipherment of the tRNA's operational code, known as the identity problem, requires the location of the sites in the tRNA structure that are involved in their correct recognition by the corresponding aminoacyl-tRNA synthetase. In this work, we determine the identity elements of each tRNA isoacceptor by means of the variation of information measure from information theory. We show that all isoacceptors exhibit sites associated with some bases of the anticodon. These sites form clusters that are scattered along the tRNA structure. The clusters determine the identity elements of each tRNA. We derive a catalogue of clustered sites for each tRNA that expands previously reported elements.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available