Journal
ORGANIC LETTERS
Volume 19, Issue 10, Pages 2502-2505Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b00730
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Funding
- National NSF of China [21432005]
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An efficient Ir-catalyzed amidation of indoles with sulfonyl azides is disclosed, affording diverse C4-amidated indoles exclusively under mild conditions. In this protocol, a variety of indoles with commonly occurring functional groups such as formyl, acetyl, carboxyl, amide, and ester at the C3 position are well tolerated.
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