4.8 Article

Synthesis of Fused Pyran Derivatives via Visible-Light-Induced Cascade Cyclization of 1,7-Enynes with Acyl Chlorides

Journal

ORGANIC LETTERS
Volume 19, Issue 3, Pages 512-515

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b03684

Keywords

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Funding

  1. NSFC [21632003, 21302075, 21372105, 21572087]
  2. International S&T Cooperation Program of China [2013DFR70580]
  3. 111program from the MOE of P. R. China

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A photocatalytic cascade cyclization of 1,7-enynes with acyl chlorides has been established. This method offers an operationally simple access to diverse fused pyran derivatives with a broad substrate scope in high yields from simple acyl chlorides via an acyl radical intermediate.

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