Journal
ORGANIC LETTERS
Volume 19, Issue 11, Pages 2825-2828Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b00980
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Funding
- National Key Research and Development Program of China [2016YFA0602900]
- National Natural Science Foundation of China [21672072, 21472051, 21490572]
- Pearl River S&T Nova Program of Guangzhou [201610010160]
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A convenient protocol for the synthesis of sulfonylated benzofurans via Ag-catalyzed oxidative cyclization has been established. Chemically stable and easily available sodium sulfinates were used as the sulfonylation reagents and building block for the heterocycle construction. With this novel strategy, various benzofurans bearing dual functional groups could be obtained in good yields with high chemo- and regioselectivities under mild conditions.
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