Journal
ORGANIC LETTERS
Volume 19, Issue 22, Pages 6260-6263Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b03331
Keywords
-
Categories
Funding
- CAS Interdisciplinary Innovation Team
- National Natural Science Foundation of China [21672199, 21702197]
- Fundamental Research Funds for the Central Universities
- Anhui Provincial Natural Science Foundation [1708085MB28]
Ask authors/readers for more resources
An efficient strategy for the cleavage of the CN bond of tertiary amines was developed with DTBP as an oxidant, in which the cleaved H atom and amine moiety were successfully transferred to the desired products. This strategy has enabled an efficient palladium-catalyzed hydroaminocarbonylation of alkynes with tertiary amines. Notably, the catalyst loading could be lowered from 5 to 0.1 mol %, which represents the lowest catalyst loading among the reported work on carbonylation via CN bond activation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
