Journal
ORGANIC LETTERS
Volume 19, Issue 16, Pages 4351-4354Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b02044
Keywords
-
Categories
Funding
- NSFC [21432003, 81473095, 21602091]
- Program for Chang-jiang Scholars and Innovative Research Team in University (PCSIRT) [IRT_15R27]
- Fundamental Research Funds for the Central Universities [lzujbky-2016-ct01, lzujbky-2017-k11, lzujbky-2015-k11, lzujbky-2017-19, lzujbky-2017-118]
Ask authors/readers for more resources
A magnesium catalyzed asymmetric conjugate reaction of C3-pyrrolyl-oxindoles with terminal alkynones is presented. The current asymmetric conjugate reaction relies on the development of novel combinational magnesium catalysis involving two chiral ligands. The current protocol proceeds smoothly and gives the corresponding enantioenriched 3,3-disubstituted oxindole skeletons with good enantioselectivities. Furthermore, the conjugate adducts could be transferred to spiro oixndole structures containing an eight membered ring in high ee Values.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available