Journal
ORGANIC LETTERS
Volume 19, Issue 12, Pages 3219-3222Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b01336
Keywords
-
Categories
Funding
- NSFC [21372002, 21232007]
- Natural Science Foundation of Jiangsu Province [BK20160003]
- PAPD
Ask authors/readers for more resources
The first catalytic asymmetric construction of the tryptanthrin skeleton has been established, taking advantage of a palladium(0)/chiral ligand-catalyzed enantioselective decarboxylative [4 + 2] cyclization of vinyl benzoxazinanones with isatins. This reaction has not only provided a direct and efficient method for constructing chiral tryptanthrin skeleta in high yields and excellent enantioselectivities (up to 97% yield, >99% ee) but also represents the first catalytic asymmetric decarboxylative cyclization of vinyl benzoxazinanones with isatins.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available