Journal
ORGANIC LETTERS
Volume 19, Issue 14, Pages 3819-3822Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b01693
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Funding
- National Institutes of Health [1F31HL137233]
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Sulfinic acids are commonly encountered intermediates found in natural product synthesis and medicinal chemistry. However, because of high reactivity, instability; and harsh reaction conditions, they are difficult to synthesize. Herein we have developed an Oxidation-free method to produce sulfinic acids and sulfinate salts,using 2-sulfinyl benzothiazole (BTS). We have, also demonstratd the synthetic usefulness by developing one-pot syntheses of sulfones and sulfonamides.
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