4.8 Article

A Metal-Free Route to Heterocyclic Trifluoromethyl- and Fluoroalkylselenolated Molecules

Journal

ORGANIC LETTERS
Volume 20, Issue 1, Pages 56-59

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b03338

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Funding

  1. Centre National de la Recherche Scientifique (CNRS), France
  2. French Ministry of Research
  3. French Fluorine Network (GIS Fluor)

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A metal-free methodology to easily synthesize various CF3Se-containing heterocyclic compounds has been developed through intramolecular ring closures of alkynes promoted with CF3SeCl. Moreover, this strategy has also been extended to other fluoroalkylselenyl groups.

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