Journal
ORGANIC LETTERS
Volume 19, Issue 13, Pages 3498-3501Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b01474
Keywords
-
Categories
Funding
- University of Warwick
- Warwick URSS scheme
- Royal Society
Ask authors/readers for more resources
We report a transition-metal-free coupling of aldehydes and ketones with geminal bis(boron) building blocks. which provides the coupled, homologated carbonyl compound, upon oxidation. This reaction not only extends an alkyl chain containing a carbonyl group, it also simultaneously introduces anew carbonyl substituent. We demonstrate that enantiopure aldehydes with an enolizable stereogenic center undergo this reaction with complete retention of stereochemistry.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available